3760-63-2

Basic information

• Product Name: 4-Dimethylamino-1-phenyl-1-butanone
• Synonyms: 4-Dimethylamino-1-phenyl-1-butanone;γ-(Dimethylamino)butyrophenone;4-(dimethylamino)-1-phenylbutan-1-one
• CAS NO: 3760-63-2
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.27
• Mol File: 3760-63-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 139-141 °C(Press: 5 Torr)
• Appearance: /
• Density: 0.984±0.06 g/cm3(Predicted)
• PKA: 9.40±0.28(Predicted)
• CAS DataBase Reference: 4-Dimethylamino-1-phenyl-1-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Dimethylamino-1-phenyl-1-butanone(3760-63-2)
• EPA Substance Registry System: 4-Dimethylamino-1-phenyl-1-butanone(3760-63-2)

Safety Data

• Hazardous Substances Data: 3760-63-2(Hazardous Substances Data)

Upstream product

• 100-47-0 benzonitrile 
• 1202-55-7 4-phenyl-1-(N,N-dimethylamino)butane 
• 120615-47-6 3-dimethylaminopropylmagnesiumbromide 
• 124-40-3 dimethyl amine 
• 939-52-6 4-chloro-1-phenylbutan-1-one 
• 69954-66-1 4-(dimethylamino)butyric acid hydrochloride 
• 71-43-2 benzene 

Downstream Products

• 43018-74-2 1-p-Chlorphenoxy-5-dimethylamino-pentanol-⁽²⁾ 
• 26307-34-6 4-Dimethylamino-2-benzyl-1-phenylbutan-1-on 
• 691412-28-9 N,N-dimethyl-2-(5-fluoro-2-phenylindol-3-yl)ethylamine 
• 26307-37-9 4-Dimethylamino-2-(4-methyl-benzyl)-1-phenyl-butan-1-one 
• 5554-67-6 4-dimethylamino-1-phenyl-butan-1-ol 
• 4560-13-8 dimethyl-[2-(2-phenyl-indol-3-yl)-ethyl]-amine 

Relevant articles and documents

Remote C(sp3)-H Oxygenation of Protonated Aliphatic Amines with Potassium Persulfate

This letter describes the development of a method for selective remote C(sp3)-H oxygenation of protonated aliphatic amines using aqueous potassium persulfate. Protonation serves to deactivate the proximal C(sp3)-H bonds of the amine substrates and also renders the amines soluble in the aqueous medium. These reactions proceed under relatively mild conditions (within 2 h at 80 °C with amine as limiting reagent) and do not require a transition metal catalyst. This method is applicable to a variety of types of C(sp3)-H bonds, including 3°, 2°, and benzylic C-H sites in primary, secondary, and tertiary amine substrates.

Asymmetric synthesis of α-N,N-dialkylamino alcohols by transfer hydrogenation of N,N-dialkylamino ketones

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