37620-61-4

Basic information

• Product Name: 5-methyl-3-(p-tolyl)-2,3-dihydro-1H-inden-1-one
• Synonyms: 5-methyl-3-(p-tolyl)-2,3-dihydro-1H-inden-1-one
• CAS NO: 37620-61-4
• Molecular Weight: 236.313
• Mol File: 37620-61-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-methyl-3-(p-tolyl)-2,3-dihydro-1H-inden-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-3-(p-tolyl)-2,3-dihydro-1H-inden-1-one(37620-61-4)
• EPA Substance Registry System: 5-methyl-3-(p-tolyl)-2,3-dihydro-1H-inden-1-one(37620-61-4)

Safety Data

• Hazardous Substances Data: 37620-61-4(Hazardous Substances Data)

Upstream product

• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 68185-94-4 trimethyl-4-methylbenzoylsilane 
• 4186-14-5 1-(2-(trimethylsilyl)ethynyl)toluene 

Relevant articles and documents

Gold(I)-Catalyzed Addition of Silylacetylenes to Acylsilanes: Synthesis of Indanones by C-H Functionalization through a Gold(I) Carbenoid

A gold(I)-catalyzed synthesis of indanones from trimethylsilylacetylenes and acylsilanes is presented. The reaction is initiated through a synergistic acylsilane activation-gold acetylide formation and involves consecutive alkyne σ-gold(I) addition, π-activation, and 1,2-migration of a silyl group. Studies performed on the reaction mechanism allowed to establish the nature of the silyl migrating group and invoke the participation of a gold(I) carbenoid intermediate. The reaction is completed by a gold(I) C-H functionalization step.