376583-97-0

Upstream product

• 501-53-1 benzyl chloroformate 
• 376583-96-9 3-amino-5-[4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-1-methyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one 
• 412317-51-2 5-[4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-5-hydroxy-1-methyl-2-oxo-1,2,3,5-tetrahydro-benzo[e][1,4]diazepine-4-carboxylic acid tert-butyl ester 
• 376583-94-7 5-[4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-1-methyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one 
• 170284-66-9 1-methyl-2,5-dioxo-1,2,3,5-tetrahydro-benzo[e][1,4]diazepine-4-carboxylic acid tert-butyl ester 
• 5946-42-9 methyl 2-(N-bromoacetyl-N-methylamino)benzoate 
• 1133-42-2 1-methyl-1,2,3,4-tetrahydro-3H-1,4-benzodiazepin-2,5-dione 
• 85-91-6 Methyl N-methylanthranilate 

Relevant academic research and scientific papers

A new series of potent benzodiazepine gamma-secretase inhibitors.

A new series of benzodiazepine-containing gamma-secretase inhibitors with potential use in the treatment of Alzheimer's disease is disclosed. Structure-activity relationships of the pendant hydrocinnamate side-chain which led to the preparation of highly