376592-57-3 Usage
Uses
Used in Organic Synthesis:
[1,1'-Biphenyl]-3-carboxylic acid, 5'-chloro-2'-hydroxyis used as an intermediate in organic synthesis for the preparation of various chemical compounds. Its unique structure allows for further reactions and modifications, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, [1,1'-Biphenyl]-3-carboxylic acid, 5'-chloro-2'-hydroxyis used as a building block for the development of new drugs. Its functional groups can be exploited to create molecules with specific biological activities, potentially leading to the discovery of novel therapeutic agents.
Used in Chemical Research:
[1,1'-Biphenyl]-3-carboxylic acid, 5'-chloro-2'-hydroxyis also used in chemical research as a model compound to study the properties and reactivity of organochlorine compounds. This can provide insights into the behavior of similar compounds and contribute to the broader understanding of chemical reactions and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 376592-57-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,6,5,9 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 376592-57:
(8*3)+(7*7)+(6*6)+(5*5)+(4*9)+(3*2)+(2*5)+(1*7)=193
193 % 10 = 3
So 376592-57-3 is a valid CAS Registry Number.
376592-57-3Relevant academic research and scientific papers
PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR THE SYNTHESIS OF ELTROMBOPAG OR SALT THEREOF
-
Paragraph 00133, (2021/01/23)
Object of the present invention is an improved process for the preparation of key intermediates for the synthesis of Eltrombopag, passing through/using intermediate 5'-Chloro-2'-hydroxy[1,1'-biphenyl]-3-carboxylic acid alkaline metal salt of formula: wherein A is an alkaline metal.
PROCESSES FOR THE PREPARATION OF AN INTERMEDIATE IN THE SYNTHESIS OF ELTROMBOPAG
-
Paragraph 0050, (2013/04/13)
3'-Amino-2'-hydroxybiphenyl-3-carboxylic acid (BPCA) and related compounds have been prepared using compounds such as: wherein R1 is -H, -Cl or -F; R2 is -Br or -I; and R3 is -H or -N02. BPCA is useful, for example, in the preparation of Eltrombopag.
Thrombopoietin mimetics
-
Page 22, (2008/06/13)
Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
