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5-Chloro-2-hydroxy-3-nitro-(1,1-biphenyl)-3-carboxylic acid is a complex organic chemical substance featuring a biphenyl structure with two phenyl rings linked by a carbon-carbon bond. 5-Chloro-2-hydroxy-3-nitro-(1,1-biphenyl)-3-carboxylic acid is distinguished by the presence of a carboxylic acid, a nitro group, and a hydroxyl group, which collectively influence its chemical behavior and reactivity. The chlorination of the molecule may also suggest potential environmental and health concerns, necessitating careful handling.

376592-58-4

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376592-58-4 Usage

Uses

Used in Chemical Synthesis:
5-Chloro-2-hydroxy-3-nitro-(1,1-biphenyl)-3-carboxylic acid is used as a building block in the synthesis of various organic compounds, leveraging its multiple functional groups for further chemical reactions and the creation of new molecules with specific properties.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 5-Chloro-2-hydroxy-3-nitro-(1,1-biphenyl)-3-carboxylic acid is utilized as an intermediate in the development of drugs, potentially contributing to the synthesis of novel therapeutic agents due to its unique structural features.
Used in Material Science:
5-Chloro-2-hydroxy-3-nitro-(1,1-biphenyl)-3-carboxylic acid may be employed in material science for the development of new polymers or composite materials, where its structural components could influence the physical and chemical properties of the final product.
Used in Environmental Applications:
Given its chlorinated nature, 5-Chloro-2-hydroxy-3-nitro-(1,1-biphenyl)-3-carboxylic acid could be studied for its potential use in environmental remediation processes, such as the degradation of pollutants or the development of new, eco-friendly materials.
Used in Research and Development:
In academic and industrial research settings, 5-Chloro-2-hydroxy-3-nitro-(1,1-biphenyl)-3-carboxylic acid serves as a subject of study to explore its chemical properties, reactivity, and potential applications in various fields, including but not limited to medicine, materials science, and environmental science.

Check Digit Verification of cas no

The CAS Registry Mumber 376592-58-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,6,5,9 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 376592-58:
(8*3)+(7*7)+(6*6)+(5*5)+(4*9)+(3*2)+(2*5)+(1*8)=194
194 % 10 = 4
So 376592-58-4 is a valid CAS Registry Number.

376592-58-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(5-chloro-2-hydroxy-3-nitrophenyl)benzoic acid

1.2 Other means of identification

Product number -
Other names 5'-chloro-2'-hydroxy-3'-nitrobiphenyl-3-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:376592-58-4 SDS

376592-58-4Relevant academic research and scientific papers

PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR THE SYNTHESIS OF ELTROMBOPAG OR SALT THEREOF

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, (2021/01/23)

Object of the present invention is an improved process for the preparation of key intermediates for the synthesis of Eltrombopag, passing through/using intermediate 5'-Chloro-2'-hydroxy[1,1'-biphenyl]-3-carboxylic acid alkaline metal salt of formula: wherein A is an alkaline metal.

PROCESSES FOR THE PREPARATION OF AN INTERMEDIATE IN THE SYNTHESIS OF ELTROMBOPAG

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, (2013/04/13)

3'-Amino-2'-hydroxybiphenyl-3-carboxylic acid (BPCA) and related compounds have been prepared using compounds such as: wherein R1 is -H, -Cl or -F; R2 is -Br or -I; and R3 is -H or -N02. BPCA is useful, for example, in the preparation of Eltrombopag.

Thrombopoietin mimetics

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Page 22, (2008/06/13)

Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.

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