37670-56-7Relevant academic research and scientific papers
The application of vinylogous iminium salts and related synthons to the regiocontrolled preparation of 2,3- and 2,5-disubstituted pyrroles
Gupton, John T.,Petrich, Scott A.,Smith, Lana L.,Bruce, Marc A.,Vu, Phong,Du, Karen X.,Dueno, Eric E.,Jones, Claude R.,Sikorski, James A.
, p. 6879 - 6892 (2007/10/03)
The reaction of 1-substituted vinamidinium salts with sarcosine ethyl ester produced 2,3-disubstituted pyrroles; a similar reaction with glycine ethyl ester gave 2,5-disubstituted pyrroles. Reactions of related three-carbon synthons with sarcosine and gly
An Efficient, Regiocontrolled Synthesis of 5-Aryl-2-carbethoxypyrroles from 3-Aryl-3-chloropropeniminium Salts
Gupton, John T.,Krolikowski, Dale A.,Yu, Richard H.,Vu, Phong,Sirkorski, James A.,et al.
, p. 5480 - 5483 (2007/10/02)
A variety of 3-aryl-3-chloropropeniminium salts react with α-amino acid esters under basic conditions to produce 2-carbethoxy-5-arylpyrroles in a regioselective manner.The overall process represents a short, efficient, and convergent synthesis of 2,5-disu
