65117-64-8

Basic information

• Product Name: 1H-Pyrrole-2-carboxylic acid, 5-(4-chlorophenyl)-, ethyl ester
• CAS NO: 65117-64-8
• Molecular Formula: C13H12ClNO2
• Molecular Weight: 249.697
• Mol File: 65117-64-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-2-carboxylic acid, 5-(4-chlorophenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2-carboxylic acid, 5-(4-chlorophenyl)-, ethyl ester(65117-64-8)
• EPA Substance Registry System: 1H-Pyrrole-2-carboxylic acid, 5-(4-chlorophenyl)-, ethyl ester(65117-64-8)

Safety Data

• Hazardous Substances Data: 65117-64-8(Hazardous Substances Data)

Upstream product

• 153783-24-5 (S)-5-(4-Chloro-phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylic acid ethyl ester 
• 459-73-4 GlyOEt*HCl 
• 84-58-2 2,3-dicyano-5,6-dichloro-p-benzoquinone 
• 623-33-6 glycine ethyl ester hydrochloride 
• 91193-23-6 O-ethyl S-2-(4-chlorophenyl)-2-oxoethyl carbonodithioate 
• 500801-00-3 2-ethanesulfonylamino-acrylic acid ethyl ester 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 153783-19-8 (S)-2-tert-Butoxycarbonylamino-5-(4-chloro-phenyl)-5-oxo-pentanoic acid ethyl ester 

Downstream Products

• 37670-56-7 2-carbethoxy-5-(4-chlorophenyl)-1-methylpyrrole 

Relevant articles and documents

A new synthesis of pyrroles

The radical reaction between an N-ethylsulfonylenamide and an α-xanthyl ketone gives an intermediate γ-keto imine which spontaneously ring-closes to the pyrrole.

Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole fungicidal agents

Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole compounds which are effective for the phytopathogenic fungi are described. A method for the fungicidal use of said compounds and methods for the preparation of said compounds are presented.

General method for the synthesis of 5-arylpyrrole-2-carboxylic acids

5-Arylpyrrole-2-carboxylic acids are prepared by DDQ oxidative aromatization of the corresponding ethyl 2-aryl-Δ1-pyrroline-5-carboxylate followed by basic hydrolysis.