37692-09-4

Upstream product

• 106-49-0 p-toluidine 
• 882-33-7 diphenyldisulfane 
• 2942-15-6 6-methylbenzothiazole 
• 591-50-4 iodobenzene 
• 583-68-6 2-bromo-p-toluidine 
• 108-98-5 thiophenol 
• 14204-24-1 N-(phenylthio)succinimide 

Downstream Products

• 62705-76-4 C,C,C-Trifluoro-N-(4-methyl-2-phenylsulfanyl-phenyl)-methanesulfonamide 
• 16587-52-3 3-methyl-dibenzothiophene 
• 62677-32-1 N-(2-Benzenesulfonyl-4-methyl-phenyl)-C,C,C-trifluoro-methanesulfonamide 
• 62677-45-6 N-(2-Benzenesulfinyl-4-methyl-phenyl)-C,C,C-trifluoro-methanesulfonamide 

Relevant academic research and scientific papers

Arylthiolation of arylamine derivatives with (arylthio)-pyrrolidine-2,5-diones

A simple and efficient method for arylthiolation of arylamines has been developed. The protocol uses (arylthio)pyrrolidine-2,5-diones as the arylthiolating reagents, acetonitrile as the solvent, and no catalyst and additive are required, which avoids contamination from the transition metal catalysts in the target products. Therefore, the present method should provide a convenient, efficient and practical strategy for the synthesis of other aryl sulfides.

An efficient heterogeneous Cu-grafted mesoporous organosilicas nanocatalyst for two and three component C-S coupling reactions

Furfural-imine functionalized mesoporous organosilica material has been synthesized by postsynthesis surface functionalization of 2D-hexagnoal mesoporous SBA-15 with organosilane precursor 3-aminopropyltriethoxy-silane (APTES) followed by Schiff-base condensation with furfural. On the other hand, furfural-imine functionalized MCM-41 has been synthesized by Schiff-base condensation of furfural and 3-aminopropyltriethoxy-silane (APTES) followed by its hydrothermal co-condensation with tetraethylorthosilicate (TEOS) in the presence of a cationic surfactant CTAB. Subsequent reaction of the imine-functionalized mesoporous organosilicas with Cu(OAc)2 in absolute ethanol produced Cu(II)-grafted mesoporous nanocatalysts 1 and 2, respectively. Powder XRD, HR TEM, FE SEM, N2 sorption and EPR experimental tolls are employed to characterize these Cu-grafted furfural-imine functionalized nanocatalysts. Cu-grafted MCM-41 (1) showed very good catalytic efficiency for the coupling of aryl bromides and thiophenol under aerobic conditions to produce different thioethers. On the other hand, Cu-anchored mesoporous SBA-15 nanocatalyst (2) exhibited high catalytic activity for one-pot three component coupling of different aryl halides with thiourea and benzyl bromide in aqueous medium to produce different aryl alkyl thioethers in very good yields. Both Cu-grafted mesoporous nanocatalysts can be efficiently reused for several reaction cycles. Copyright

Copper powder catalyzed direct ring-opening arylation of benzazoles with aryl iodides in polyethylene glycol

The expedient and efficient copper powder catalyzed direct ring-opening arylation of benzazoles with aryl iodides in polyethylene glycol that proceeds in the absence of an added ligand has been developed. The protocol provides facile access to 2-(arylthio)anilines and 2-phenoxyanilines in high yields with a wide tolerance of functional groups. Transmission electron microscopy confirmed that the active catalyst results from the in situ generation of copper nanoparticles under standard reaction conditions, which is an alternative avenue to develop a highly effective metallic copper catalyst. Moreover, the catalytic system can be recycled up to six times. Copyright

FeF3/i2-catalyzed synthesis of 4-chalcogen- substituted arylamines by direct thiolation of an arene C-H bond

An efficient regioselective synthesis of 4-chalcogen-substituted-arylamines by FeF3-catalyzed sulfenylation and selenation of arylamines has been developed. In the presence of FeF3and I2, a variety of arylamines underwent the reaction with disulfides or diselenides to afford the corresponding 4-sulfenyl-or 4-selenenyl-arylamines in moderate to good yields. Georg Thieme Verlag Stuttgart.