37696-14-3

Upstream product

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 75-07-0 acetaldehyde 

Downstream Products

• 89578-36-9 (1¹S,4R)-4-methyl-1-(α-methylbenzyl)azetidin-2-one 
• 26757-80-2 (1¹S,4S)-4-methyl-1-(α-methylbenzyl)azetidin-2-one 
• 42492-96-6 (R)-2-((S)-1-Phenyl-ethylamino)-propionitrile 
• 68779-55-5 (R)-2-((S)-1-Phenyl-ethylamino)-propionic acid 

Relevant academic research and scientific papers

Asymmetric Syntheses of Amino Acids by Addition of Cyanide to the Schiff Bases in the Presence of Cyanide-Modified Hemin-Copolymer

Sterically controlled addition reactions of CN group to the Schiff bases by using CN-modified hemin-copolymer were carried out, and the optical yields (80-95 e.e.) of the resulting amino acids were much higher than that obtained without hemin-copolymer.

Diastereoface-Differentiating Synthesis of Substituted β-Lactams from Chiral Imines and/or Chiral α-Chloro Iminium Chlorides

Reaction of imines carrying a chiral substituent at a nitrogen atom with symmetric or prochiral α-chloro iminium chlorides leads in a diastereoface-differentiating reaction to a mixture of diatereoisomeric or epimeric β-lactams.Attempts were made to determine the absolute configuration of obtained chiral β-lactams.Reaction of prochiral imines with chiral α-chloro iminium chlorides also provides mixtures of diastereomeric β-lactams or their enantiomers with a clear selectivity.

ASYMMETRIC ADDITION OF TRIS(TRIMETHYLSILYL) PHOSPHITE TO CHIRAL ALDIMINES

Addition of tris(trimethylsilyl) phosphite (2) to (+)-(R)-1-phenylethylaldimines (1) and methanolysis of addition products affords(+)-N-(1-phenyethyl)-1-aminoalkanophosphonic acids (3).Chemical yields and diastereomeric composition of 3 vary from 10 to 90