3774-64-9

Basic information

• Product Name: questin
• Synonyms: questin;1,6-Dihydroxy-3-methyl-8-methoxy-9,10-anthraquinone;1,6-Dihydroxy-8-methoxy-3-methyl-9,10-anthracenedione
• CAS NO: 3774-64-9
• Molecular Formula: C₁₆H₁₂O₅
• Molecular Weight: 284.26
• Mol File: 3774-64-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 301-303 °C
• Boiling Point: 557°Cat760mmHg
• Flash Point: 213.9°C
• Appearance: /
• Density: 1.448g/cm³
• Vapor Pressure: 5.15E-13mmHg at 25°C
• Refractive Index: 1.677
• PKA: 6.50±0.20(Predicted)
• CAS DataBase Reference: questin(CAS DataBase Reference)
• NIST Chemistry Reference: questin(3774-64-9)
• EPA Substance Registry System: questin(3774-64-9)

Safety Data

• Hazardous Substances Data: 3774-64-9(Hazardous Substances Data)

Usage

General Description

Questin is a chemical compound that is a colorless, odorless liquid used as a solvent and in the production of pesticides. It is classified as a hazardous substance and is known to be harmful if swallowed, inhaled, or comes into contact with skin. Questin is also considered to be a potential environmental hazard, as it can contaminate water and soil. It is important to handle questin with caution and follow safety guidelines to prevent any negative impact on human health and the environment.

InChI:InChI=1/C16H12O5/c1-7-3-9-13(11(18)4-7)16(20)14-10(15(9)19)5-8(17)6-12(14)21-2/h3-6,17-18H,1-2H3

Upstream product

• 518-82-1 1,6,8-trihydroxy-3-methyl-9,10-anthraquinone 
• 74-88-4 methyl iodide 
• 61539-64-8 4-Chlor-1,6-dihydroxy-8-methoxy-3-methylanthraquinon 

Downstream Products

• 59092-92-1 desmethylsulochrin 
• 518-82-1 1,6,8-trihydroxy-3-methyl-9,10-anthraquinone 
• 38371-02-7 emodin-9-anthrone 

Relevant articles and documents

Characterization of emodin metabolites in Raji cells by LC-APCI-MS/MS

A rapid, simple, and sensitive liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry (LC-APCI-MS/MS) method was developed for the identification and quantification of emodin metabolites in Raji cells, using aloe-emodin as an internal standard. Analyses were performed on an LC system employing a Cosmosil 5C18 AR-II column and a stepwise gradient elution with methanol-20 mM ammonium formate at a flow rate of 1.0 mL/min operating in the negative ion mode. As a result, the starting material emodin and its five metabolites were detected by analyzing extracts of Raji cells that had been cultivated in the presence of emodin. The identification of the metabolites and elucidation of their structures were performed by comparing their retention times and spectral patterns with those of synthetic samples. In addition to the major metabolite 8-O-methylemodin, four other metabolites were assigned as ω-hydroxyemodin, 3-O-methyl-ω-hydroxyemodin, 3-O-methylemodin (physcion), and chrysophanol.