37748-08-6

Upstream product

• 37748-11-1 [3-(hydroxymethyl)phenoxy]acetic acid methyl ester 
• 100-83-4 meta-hydroxybenzaldehyde 
• 37748-10-0 methyl (3-formylphenoxy)acetate 

Downstream Products

• 98892-41-2 {3-[(1R,2S,3S,4S)-3-((R)-3-Hydroxy-oct-1-ynyl)-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl]-phenoxy}-acetic acid 
• 98892-38-7 {3-[(1S,2R,3R,4R)-3-((R)-3-Hydroxy-oct-1-ynyl)-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl]-phenoxy}-acetic acid methyl ester 
• 98892-41-2 {3-[(1S,2R,3R,4R)-3-((R)-3-Hydroxy-oct-1-ynyl)-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl]-phenoxy}-acetic acid 
• 98892-38-7 {3-[(1R,2S,3S,4S)-3-((R)-3-Hydroxy-oct-1-ynyl)-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl]-phenoxy}-acetic acid methyl ester 
• 113332-13-1 {3-[(1S,2S,3S,4R,1'S,3'R,4'R)-3'-((S)-3-Hydroxy-oct-1-ynyl)-[2,2']bi[7-oxa-bicyclo[2.2.1]heptyl]-3-ylmethyl]-phenoxy}-acetic acid methyl ester 
• 113332-13-1 {3-[(1S,3S,4R,1'S,2'R,3'R,4'R)-3'-((R)-3-Hydroxy-oct-1-ynyl)-[2,2']bi[7-oxa-bicyclo[2.2.1]heptyl]-3-ylmethyl]-phenoxy}-acetic acid methyl ester 
• 98892-39-8 {3-[(1S,2R,3S,4R)-3-((R)-3-Hydroxy-oct-1-ynyl)-bicyclo[2.2.1]hept-2-ylmethyl]-phenoxy}-acetic acid 
• 98892-36-5 {3-[(1R,2S,3R,4S)-3-((R)-3-Hydroxy-oct-1-ynyl)-bicyclo[2.2.1]hept-2-ylmethyl]-phenoxy}-acetic acid methyl ester 
• 98892-39-8 {3-[(1R,2S,3R,4S)-3-((R)-3-Hydroxy-oct-1-ynyl)-bicyclo[2.2.1]hept-2-ylmethyl]-phenoxy}-acetic acid 
• 98892-36-5 {3-[(1S,2R,3S,4R)-3-((R)-3-Hydroxy-oct-1-ynyl)-bicyclo[2.2.1]hept-2-ylmethyl]-phenoxy}-acetic acid methyl ester 
• 98892-36-5 {3-[(1S,2R,3S,4R)-3-((S)-3-Hydroxy-oct-1-ynyl)-bicyclo[2.2.1]hept-2-ylmethyl]-phenoxy}-acetic acid methyl ester 
• 98892-37-6 {3-[(1R,2R,3S,4S)-3-((S)-3-Hydroxy-oct-1-ynyl)-bicyclo[2.2.1]hept-5-en-2-ylmethyl]-phenoxy}-acetic acid methyl ester 
• 98892-38-7 {3-[(1R,2S,3S,4S)-3-((S)-3-Hydroxy-oct-1-ynyl)-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl]-phenoxy}-acetic acid methyl ester 
• 98892-40-1 {3-[(1R,2R,3S,4S)-3-((R)-3-Hydroxy-oct-1-ynyl)-bicyclo[2.2.1]hept-5-en-2-ylmethyl]-phenoxy}-acetic acid 

Relevant academic research and scientific papers

Organopalladium Approaches to Prostaglandins. 6. Synthesis of Interphenylene Prostaglandin Endoperoxide Analogs Via Benzylpalladation of Bicyclic Alkenes.

The reactions of norbornene, norbornadiene and 7-oxanorbornene with methyl 3-(chloromethyl)phenoxyacetate (4), optically pure (S)-1-octyn-3-ol (5), and 8percent Pd(PPh3)4 afford in one step satisfactory yields of the corresponding esters 6, 7 and 8 respectively, readily saponified to the first interphenylene prostaglandin endoperoxide analogs 10, 11 and 12 respectively.

PGE1 -oxa phenylene compounds

This invention is a group of PGE1 -type oxa-phenylene compounds, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

PGEo oxa-phenylene compounds

This invention is a group of 13,14-dihydro-PGE1 -type (also referred to as PGEo -type) oxa-phenylene compounds, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

PGA1 -oxa-phenylene compounds

This invention is a group of PGA1 -type oxa-phenylene compounds, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, treatment of asthma, and management of renal dysfuction.

PGE2 -oxa-phenylene compounds

This invention is a group of PGE2 -type oxa-phenylene compounds, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

Oxa-phenylene compounds

This invention is a group of 17,18-didehydro-PG1 - and -PG2 -type oxa-phenylene compounds, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

PGF1β -oxa phenylene compounds

This invention is a group of PGF1β -type and PGF2β -type oxa-phenylene compounds, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including inhibition of platelet aggregation, treatment of asthma, labor inducement at term, and cervical dilation.

PGF1α -oxaphenylene compounds

This invention is a group of PGF1α -type oxaphenylene compounds, and processes for making them. These compounds are useful for a variety of pharamcological purposes, including inhibition of platelet aggregation, treatment of asthma, labor inducement at term, and cervical dilation.