37748-10-0

Basic information

• Product Name: methyl (3-formylphenoxy)acetate
• Synonyms: methyl (3-formylphenoxy)acetate;Methyl 2-(3-formylphenoxy)acetate;2-(3-formylphenoxy)Acetic acid methyl ester
• CAS NO: 37748-10-0
• Molecular Formula: C₁₀H₁₀O₄
• Molecular Weight: 194.19
• Mol File: 37748-10-0.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 307.4 °C at 760 mmHg
• Flash Point: 135.1 °C
• Appearance: /
• Density: 1.201 g/cm³
• Vapor Pressure: 0.000729mmHg at 25°C
• Refractive Index: 1.54
• Storage Temp.: 2-8°C
• CAS DataBase Reference: methyl (3-formylphenoxy)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (3-formylphenoxy)acetate(37748-10-0)
• EPA Substance Registry System: methyl (3-formylphenoxy)acetate(37748-10-0)

Safety Data

• Hazardous Substances Data: 37748-10-0(Hazardous Substances Data)

Usage

General Description

Methyl (3-formylphenoxy)acetate, also known as 3-(methoxycarbonyl)phenyl formate, is a chemical compound with the molecular formula C10H10O4. It is a clear liquid with a faint, sweet odor. Methyl (3-formylphenoxy)acetate is commonly used as a fragrance ingredient and a flavoring agent in the food and beverage industry. It is also used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. methyl (3-formylphenoxy)acetate has potential applications in the production of cosmetics, perfumes, and household products. However, it should be handled with care as it may cause skin and eye irritation, and inhalation of its vapors may cause respiratory irritation. Overall, methyl (3-formylphenoxy)acetate is a versatile chemical with a variety of uses but should be used with proper safety precautions.

InChI:InChI=1/C10H10O4/c1-13-10(12)7-14-9-4-2-3-8(5-9)6-11/h2-6H,7H2,1H3

Upstream product

• 96-32-2 bromoacetic acid methyl ester 
• 100-83-4 meta-hydroxybenzaldehyde 
• 96-34-4 methyl chloroacetate 
• 37748-09-7 2-(3-formylphenoxy)acetic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 1310696-55-9 Methyl (3-{[[3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl](3-morpholinopropyl)amino]methyl}phenoxy)acetate 
• 1310696-35-5 Methyl 2-(3-{[3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propylamino]methyl}phenoxy)acetate 
• 113496-13-2 methyl 3-carboxyphenoxyacetate 
• 1136554-92-1 C₉H₁₁N₃O₄ 

Relevant articles and documents

An Aldehyde Responsive, Cleavable Linker for Glucose Responsive Insulins

A glucose responsive insulin (GRI) that responds to changes in blood glucose concentrations has remained an elusive goal. Here we describe the development of glucose cleavable linkers based on hydrazone and thiazolidine structures. We developed linkers with low levels of spontaneous hydrolysis but increased level of hydrolysis with rising concentrations of glucose, which demonstrated their glucose responsiveness in vitro. Lipidated hydrazones and thiazolidines were conjugated to the LysB29 side-chain of HI by pH-controlled acylations providing GRIs with glucose responsiveness confirmed in vitro for thiazolidines. Clamp studies showed increased glucose infusion at hyperglycemic conditions for one GRI indicative of a true glucose response. The glucose responsive cleavable linker in these GRIs allow changes in glucose levels to drive the release of active insulin from a circulating depot. We have demonstrated an unprecedented, chemically responsive linker concept for biopharmaceuticals.

2-PHENYL-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN TYROSINE KINASE ROR1 ACTIVITY

A compound of formula (I′) or (I′′) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of mammalian kinase enzyme activity, including ROR1 tyrosine kinase activity and may be used in the treatment of disorders associated with such activity.

Methods of treatment using an EP2 selective receptor agonist

The present invention relates to methods of treating pulmonary hypertension, facilitating joint fusion, facilitating tendon and ligament repair, reducing the occurrence of secondary fracture, treating avascular necrosis, facilitating cartilage repair, facilitating bone healing after limb transplantation, facilitating liver regeneration, facilitating wound healing, reducing the occurrence of gastric ulceration, treating hypertension, facilitating the growth of tooth enamel or finger or toe nails, treating glaucoma, treating ocular hypertension, and repairing damage caused by metastatic bone disease using an EP2 selective receptor agonist.