37748-09-7

Basic information

• Product Name: 3-FORMYLPHENOXYACETIC ACID
• Synonyms: M-FORMYLPHENOXYACETIC ACID;ASISCHEM U97635;3-FORMYLPHENOXYACETIC ACID;M-FORMYLPHENOXYACETIC ACID 97 %;TIMTEC-BB SBB008593
• CAS NO: 37748-09-7
• Molecular Formula: C₉H₈O₄
• Molecular Weight: 180.16
• Product Categories: Phenoxyacetic Acids and Alcohols (substituted)
• Mol File: 37748-09-7.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 363.3°C at 760 mmHg
• Flash Point: 150.8°C
• Appearance: /
• Density: 1.322g/cm³
• Vapor Pressure: 6.48E-06mmHg at 25°C
• Refractive Index: 1.588
• CAS DataBase Reference: 3-FORMYLPHENOXYACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-FORMYLPHENOXYACETIC ACID(37748-09-7)
• EPA Substance Registry System: 3-FORMYLPHENOXYACETIC ACID(37748-09-7)

Safety Data

• Statements: 41
• Safety Statements: 26-39
• Hazardous Substances Data: 37748-09-7(Hazardous Substances Data)

Usage

General Description

3-Formylphenoxyacetic acid is a synthetic organic compound with the chemical formula C9H8O4. It is a derivative of phenoxyacetic acid, containing an additional formyl group (CHO) attached to the phenyl ring. 3-FORMYLPHENOXYACETIC ACID is often used in the synthesis of various pharmaceuticals, agrochemicals, and dyes due to its reactive formyl group and its ability to undergo a variety of chemical reactions. It has also been studied for its potential use in the treatment of certain medical conditions, particularly in the field of cancer research. Additionally, 3-formylphenoxyacetic acid has been found to have potential applications in organic and medicinal chemistry due to its unique structure and reactivity.

InChI:InChI=1/C9H8O4/c10-5-7-2-1-3-8(4-7)13-6-9(11)12/h1-5H,6H2,(H,11,12)

Upstream product

• 51264-68-7 ethyl 2-(3-formylphenoxy)acetate 
• 186191-14-0 potassium salt of 3-(carboxymethoxy)benzaldehyde 
• 100-83-4 meta-hydroxybenzaldehyde 
• 79-08-3 bromoacetic acid 
• 96-32-2 bromoacetic acid methyl ester 
• 37748-10-0 methyl (3-formylphenoxy)acetate 
• 79-11-8 chloroacetic acid 

Downstream Products

• 51264-68-7 ethyl 2-(3-formylphenoxy)acetate 
• 875801-92-6 {3-[(E)-2-(1,3-Dimethyl-5-nitro-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin-4-yl)-vinyl]-phenoxy}-acetic acid 
• 727396-68-1 3-(tert-butyloxycarbonylmethylaminocarbonylmethoxy)-benzaldehyde 
• 1222376-93-3 (Z)-2-(3-((4-(biphenyl-2-carbonyloxy)-7-(2-methoxyphenyl)-9-oxo-5H-benzo[h]thiazolo[2,3-b]quinazolin-10(6H,7H,9H)-ylidene)methyl)phenoxy)acetic acid 
• 1222376-70-6 (Z)-2-(3-((7-(2-methoxyphenyl)-9-oxo-5H-benzo[h]thiazolo[2,3-b]quinazolin-10(6H,7H,9H)-ylidene)methyl)phenoxy)acetic acid 
• 1222376-85-3 (Z)-2-(3-((7-(3-fluorophenyl)-9-oxo-5H-benzo[h]thiazolo[2,3-b]quinazolin-10(6H,7H,9H)-ylidene)methyl)phenoxy)acetic acid 
• 1222376-87-5 (Z)-2-(3-((7-(naphthalen-1-yl)-9-oxo-5H-benzo[h]thiazolo[2,3-b]quinazolin-10(6H,7H,9H)-ylidene)methyl)phenoxy)acetic acid 
• 1222376-89-7 (Z)-2-(3-((7-(furan-2-yl)-9-oxo-5H-benzo[h]thiazolo[2,3-b]quinazolin-10(6H,7H,9H)-ylidene)methyl)phenoxy)acetic acid 
• 1222376-92-2 (Z)-2-(3-((4-(benzyloxy)-7-(2-methoxyphenyl)-9-oxo-5H-benzo[h]thiazolo[2,3-b]quinazolin-10(6H,7H,9H)-ylidene)methyl)phenoxy)acetic acid 
• 1222376-94-4 2-(3-((Z)-((E)-9-(3-fluorobenzylidene)-5-(3-fluorophenyl)-3-oxo-3,5,6,7,8,9-hexahydro-2H-thiazolo[2,3-b]quinazolin-2-ylidene)methyl)phenoxy)acetic acid 
• 1222376-95-5 (Z)-2-(3-((5-(2-methoxyphenyl)-3-oxo-7-phenyl-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidin-2-ylidene)methyl)phenoxy)acetic acid 
• 1449505-16-1 tert-butyl 4-(2-(3-formylphenoxy)acetyl)piperazine-1-carboxylate 
• 1449505-17-2 3-(2-oxo-2-(piperazin-1-yl)ethoxy)benzaldehyde 
• 1449505-18-3 3-(2-(4-(2-hydroxypropyl)piperazin-1-yl)-2-oxoethoxy)benzaldehyde 

Relevant articles and documents

NOVEL PYRIDOPYRIMIDINONE COMPOUNDS FOR MODULATING THE CATALYTIC ACTIVITY OF HISTONE LYSINE DEMETHYLASES (KDMS)

The present invention provides a compound of Formula (I) being capable of modulating the activity of histone lysine demethylase (KDM), pharmaceutical compositions thereof, methods to prepare the said compounds, and the use of such compounds as a medicament. The compound of Formula (I) acts as KDM inhibitor with marked potency, thereby having an outstanding potential for a pharmaceutical intervention of cancer and any other diseases related to KDM dysregulation.

IMIDAZO [4, 5 - B] PYRIDINE DERIVATIVES AS ALK AND JAK MODULATORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS

This application relates to compounds of the Formula I as defined herein, and/or salts thereof. This application further relates to compositions and methods of using these compounds and/or salts thereof. The compounds of Formula I are useful as ALK and JAK modulators for the treatment of proliferative disorders.

Development of an enzyme-linked immunosorbent assay for the pyrethroid insecticide cyhalothrin

A competitive enzyme-linked immunosorbent assay (ELISA) was developed for detection of the pyrethroid insecticide cyhalothrin. Three haptens with an amine or propanoic acid terminus were synthesized and then conjugated with bovine serum albumin to give immunogens. Eight polyclonal antisera produced by rabbits were screened for titers and affinity using three different coating antigens. The antiserum CWB-C had the highest affinity with cyhalothrin and a low affinity with fenvalerate, fenpropathrin, deltamethrin, and fluvalinate. The half-maximum inhibition concentration for cyhalothrin was 37.2 μg/L, and the limit of detection was 4.7 μg/L. The recoveries of different concentrations of cyhalothrin (0.1-2500 μg/L) from fortified tap water, well water, and wastewater samples as determined with the ELISA were 81-114%.