37759-80-1

Upstream product

• 308-00-9 Ethyl 3-F-heptyl 3-hydroxypropanoate 
• 335-60-4 pentadecafluoro-octanal 
• 105-53-3 diethyl malonate 
• 335-96-6 2H,2H,3H-pentadecafluoro-3-hydroxy-decanoic acid 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 3108-24-5 ethyl perfluorooctanoate 

Relevant academic research and scientific papers

Stereoselective synthesis of Z and E 3-F-alkyl 2-propenoates and derivatives

The stereoselective preparation of 3-F-alkyl 2-propenoates and their derivatives is described.E-isomers are easily obtained by an in situ reduction-olefination from esters of F-acids and phosphonates or by a convenient dehydration of 3-F-alkyl 3-hydroxyesters.Z-isomers are known to be prepared by the hydrogenation of alkynes. - Keywords: Unsaturated ester; Unsaturated nitrile; F-Alkyl Chain; Dehydration; F-Enoyl sultam

Stereoselective synthesis of F-alkyl α,β-unsaturated esters and their epoxidation

Strong electrophilic Z and E 3-F-alkyl 2-propenoates have been prepared stereoselectively. Their extremely difficult epoxidation has been achieved with retention of stereochemistry using t-BuO2Li, leading to F-alkyl glycidic esters, which are useful building blocks for the synthesis of new amphiphiles.