37784-33-1

Basic information

• Product Name: (R)-2-benzamido-2-(4-hydroxyphenyl)acetic acid
• Synonyms: (R)-2-benzamido-2-(4-hydroxyphenyl)acetic acid
• CAS NO: 37784-33-1
• Molecular Weight: 271.273
• Mol File: 37784-33-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-2-benzamido-2-(4-hydroxyphenyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-benzamido-2-(4-hydroxyphenyl)acetic acid(37784-33-1)
• EPA Substance Registry System: (R)-2-benzamido-2-(4-hydroxyphenyl)acetic acid(37784-33-1)

Safety Data

• Hazardous Substances Data: 37784-33-1(Hazardous Substances Data)

Upstream product

• 22818-40-2 D-4-hydroxyphenylglycine 
• 98-88-4 benzoyl chloride 
• 150072-82-5 4-p-Hydroxybenzyl-2-phenyloxazolin-5-on 

Downstream Products

• 851136-38-4 methyl (R)-N-benzoyl-4-methoxyphenylglycinate 

Relevant articles and documents

Cp?Co(III)/MPAA-Catalyzed Enantioselective Amidation of Ferrocenes Directed by Thioamides under Mild Conditions

Cp?Cobalt(III)-catalyzed enantioselective C-H amidation of ferrocenes using monoprotected amino acids (MPAAs) as chiral ligands was developed. The reaction was performed under mild conditions in high yields (up to 97%) with moderate enantioselectivity (up to 77.5:22.5 er), providing a promising strategy to create planar chirality via base-metal-catalyzed enantioselective C-H activation.

Synthesis of (-)-cytoxazone and (+)-epi-cytoxazone: The chiral pool approach

Immunomodulator (-)-cytoxazone and its epimer (+)-epi-cytoxazone were synthesized starting from (D)-(-)-4-hydroxyphenylglycine. Homologation of the amino acid was achieved via the corresponding aldehyde, by a cyanohydrin reaction. The racemization of high