37791-20-1

Basic information

• Product Name: iberin
• CAS NO: 37791-20-1
• Molecular Weight: 163.265
• Mol File: 37791-20-1.mol

Chemical Properties

• CAS DataBase Reference: iberin(CAS DataBase Reference)
• NIST Chemistry Reference: iberin(37791-20-1)
• EPA Substance Registry System: iberin(37791-20-1)

Safety Data

• Hazardous Substances Data: 37791-20-1(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 15813-61-3 (R)-3-methanesulfinyl-propylamine 
• 196200-06-3 3-(methylsufinyl)propan-1-amine 
• 463-71-8 thiophosgene 
• 505-79-3 iberverin 

Downstream Products

• 2455-56-3 1-[3-((R)-Methanesulfinyl)-propyl]-3-((R)-1-phenyl-ethyl)-thiourea 
• 91430-19-2 (+/-)-N-(3-methanesulfinyl-propyl)-N'-phenyl-thiourea 

Relevant articles and documents

Analysis and anti- helicobacter activity of sulforaphane and related compounds present in Broccoli (Brassica oleracea L.) sprouts

A crude methanol extract prepared from fresh broccoli sprouts was extracted with hexane, chloroform, ethyl acetate, and butanol sequentially. Residual water fraction was obtained from the residual aqueous layer. The greatest inhibition zones (>5 cm) were noted for Helicobacter pylori strain by the chloroform extract, followed by the hexane extract (5.03 cm), the ethyl acetate extract (4.90 cm), the butanol extract (3.10 cm), and the crude methanol extract (2.80 cm), whereas the residual water fraction did not show any inhibition zone. Including sulforaphane, five sulforaphane-related compounds were positively identified in the chloroform extract, of which 5- methylsulfinylpentylnitrile was found in the greatest concentration (475.7 mg/kg of fresh sprouts), followed by sulforaphane (222.6 mg/kg) and 4-methylsulfinylbutylnitrile (63.0 mg/kg). Among 18 sulforaphane and related compounds synthesized (6 amines, 6 isothiocyanates, and 6 nitriles), 2 amines, 6 isothiocyanates, and 1 nitrile exhibited >5 cm inhibitory zones for H. pylori strain. The results indicate that broccoli sprouts can be an excellent food source for medicinal substances.

BIOTRANSFORMATION OF ORGANIC SULFIDES. PART 7. FORMATION OF CHIRAL ISOTHIOCYANATO SULFOXIDES AND RELATED COMPOUNDS BY MICROBIAL BIOTRANSFORMATION

The fungi Helminthosporium species NRRL 4671 and Mortierella isabellina ATCC 42613 have been used for the biotransformation of a series of isothiocyanatoalkyl methyl sulfides and their synthetic precursors, ω-(methylthio)alkylphthalimides.H. species gave predominantly (S) sulfoxides in all cases; M. isabellina gave (R) isothiocyanatoalkyl methyl sulfoxides, but in the case of two ω-(methylthio)alkylphthalimides substantial conversion of sulfoxide to sulfone resulted in the isolation of the former with predominant (S) configuration.A correction is made of the previously reported configurations of two biotransformation products (Tetrahedron: Asymmetry, 1994, 5, 1129).