378-13-2

Usage

Uses

Used in Refrigeration Industry:
2-Chloro-1,4-dibromo-1,1,2-trifluorobutane is used as a refrigerant due to its properties that make it suitable for cooling systems. Its chemical stability and low toxicity contribute to its effectiveness in this application.
Used in Aerosol Propellants:
In the aerosol industry, 2-Chloro-1,4-dibromo-1,1,2-trifluorobutane serves as an aerosol propellant, providing the necessary pressure to dispense products such as spray paints, deodorants, and other consumer goods.
Used in Metal Coating and Finishing:
2-Chloro-1,4-dibromo-1,1,2-trifluorobutane is employed in metal coating and finishing processes, where its chemical properties aid in the application of protective layers on various metal surfaces, enhancing durability and appearance.
Used in Plastic and Polymer Production:
2-Chloro-1,4-dibromo-1,1,2-trifluorobutane is utilized in the production of plastics and polymers, where its unique structure contributes to the formation of polymer chains with specific properties, such as increased strength or resistance to certain conditions.
Used in Fire Extinguishing Systems:
2-Chloro-1,4-dibromo-1,1,2-trifluorobutane is used in fire extinguishing systems, where its chemical composition allows it to effectively suppress fires by disrupting the combustion process.

InChI:InChI=1/C4H4Br2ClF3/c5-2-1-3(7,8)4(6,9)10/h1-2H2

Upstream product

• 74-85-1 ethene 
• 354-51-8 1,2-dibromo-1-chloro-1,2,2-trifluoroethane 
• 235106-11-3 4-chloro-1,1,2-trifluorobut-1-ene 
• 178676-10-3 4-bromo-3-chloro-3,4,4-trifluorobutan-1-ol 
• 10493-44-4 1,1,2-trifluoro-4-bromobut-1-ene 

Downstream Products

• 374-25-4 4-bromo-3-chloro-3,4,4-trifluorobutene-1 

Relevant academic research and scientific papers

Synthesis method of 2-chloro-1, 4-dibromo-1, 1, 2-trifluorobutane

The invention belongs to the field of fluorine-containing fine chemical engineering, and provides a synthesis method of 2-chlorine-1, 4-dibromo-1, 1, 2-trifluorobutane. Specifically, 1, 2-dibromo-1-chloro-1, 2, 2-trifluoroethane is used as a solvent, and the 1, 2-dibromo-1-chloro-1, 2, 2-trifluoroethane reacts with ethylene in the presence of a free radical initiator containing tert-butyl peroxybenzoate (TBPB), benzoyl peroxide (BPO), lauroyl peroxide (LPO) and the like. The reaction temperature is 70-130 DEG C, and preferably, the reaction temperature is 90-120 DEG C. The molar ratio of 1, 2-dibromo-1-chloro-1, 2, 2-trifluoroethane to the initiator is 1: (0.5-1). The method reduces the content of 1, 6-dibromo-2-chloro-1, 1, 2-trifluorohexane, has the advantages of cleanness, safety and no need of solvent recovery, and is mainly used for synthesis of 2-chloro-1, 4-dibromo-1, 1, 2-trifluorobutane.

Rearrangement of 3-membered 1,1,2-trifluorobromonium and iodonium ions and comparison of trifluorochloronium to fluorocarbenium ions

(Chemical Equation Presented) Reactions of chlorine (Cl2) with 4-halo-1,1,2-trifluorobut-1-enes (1, 2, or 3) give open-ion intermediates A and E that are in equilibrium. The open-chloronium ions (E) rearrange to a five-membered-ring halonium ion during ionic chlorination of 3 when the number-4 halo-substituent is iodine. Three-membered-ring bromonium and iodonium ions from alkenes 1, 2, or 3 are rather symmetrical and similar in structure. Quantum chemical calculations show that five-membered-ring halonium ion intermediates are 11 to 27 kcal/mol more stable than the three-membered-ring halonium ions or the open-ions A and E. The five-membered-ring intermediates lead to rearranged products. Rearranged products increase as the number-4 halogen (Z) becomes more nucleophilic (Z: Cl Br I). Open chloronium ions from ionic chlorination of terminal fluorovinyl alkenes are compared to the open ions generated by protons to similar alkenes.

Copper salt-catalysed reaction of perfluoroalkyl halides with olefins

Perfluoroalkyl halides react with olefins in the presence of copper acetate and hydrazine to give 1,2-addition products.