37803-02-4

Usage

Uses

Used in Organic Synthesis:
S-2,2'-Bis(bromomethyl)-1,1'-binaphthalene is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, such as cross-coupling and substitution reactions. Its bromomethyl groups make it a versatile building block for the synthesis of complex organic molecules.
Used in Asymmetric Catalysis:
As a chiral compound, S-2,2'-Bis(bromomethyl)-1,1'-binaphthalene is used in asymmetric catalysis for preparing chiral ligands and catalysts. These chiral catalysts are essential for enantioselective synthesis, which is crucial for producing enantiomerically pure compounds with desired biological activities.
Used in Pharmaceutical Industry:
S-2,2'-Bis(bromomethyl)-1,1'-binaphthalene has been studied for its potential applications in the pharmaceutical industry. Its unique properties and reactivity make it a promising candidate for the development of new drugs and drug delivery systems.
Used in Materials Science:
In materials science, S-2,2'-Bis(bromomethyl)-1,1'-binaphthalene has potential applications in the development of new materials with specific properties. Its reactivity and chiral structure can be utilized to create materials with tailored characteristics for various applications, such as sensors, catalysts, and advanced materials for electronics and energy storage.

Upstream product

• 172748-15-1 7,22-dihydro-8,21-dioxa-tetranaphtho<2,1-b:1',2'-d:2'',1''-h:1''',2'''-j>cyclododecene 

Downstream Products

• 54130-91-5 4-(Diphenyl-phosphinoyl)-4,5-dihydro-3H-cyclohepta[2,1-a;3,4-a']dinaphthalene 
• 86631-57-4 4-((1S,2R)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-4-methyl-4,5-dihydro-3H-4-azonia-cyclohepta[2,1-a;3,4-a']dinaphthalene; bromide 
• 86593-80-8 4-((1S,2R)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-4-methyl-4,5-dihydro-3H-4-azonia-cyclohepta[2,1-a;3,4-a']dinaphthalene; bromide 
• 19634-89-0 (R)-2,2'-dimethyl-1,1'-binaphthyl 
• 32587-64-7 (S)-(+)-2,2'-dimethyl-1,1'-binaphthyl 
• 132666-12-7 4-(1-Phenyl-ethyl)-4,5-dihydro-3H-4-aza-cyclohepta[2,1-a;3,4-a']dinaphthalene 
• 132666-12-7 4-(1-Phenyl-ethyl)-4,5-dihydro-3H-4-aza-cyclohepta[2,1-a;3,4-a']dinaphthalene 
• 97590-56-2 (-)-α-<4,5-dihydro-3H-dinaphtho<2,1-c:1',2'-e>azepinyl>-α-phenylacetamide 
• 97551-07-0 (+)-α-<4,5-dihydro-3H-dinaphtho<2,1-c:1',2'-e>azepinyl>-α-phenylacetamide 
• 60536-98-3 2,2'-dimethyl-1,1'-binaphthyl 
• 188-52-3 dibenzo[c,g]phenanthrene 

Relevant academic research and scientific papers

The Williamson Reaction: A New and Efficient Method for the Alternate Reaction of 2,2'-Bis(bromomethyl)-1,1'-binaphthyl and 1,1'-Binaphthalene-2,2'-diol

Treatment of 2,2'-bis(bromomethyl)-1,1'-binaphthyl with 1,1'-binaphthalene-2,2'-diol (+)-(R)-1 and cesium or potassium carbonate in refluxing acetone, gave the diastereomeric dioxacyclophanes (-)-(R,S)-3a and (+)-(R,R)-3b, both obtained in high yield, and the cyclic tetraether (+)-(R,R,R,S)-4 as isolated side product.Boron tribromide-promoted ether cleavage of 3a and 3b gave optically pure (-)-S-2 and (+)-(R)-2, respectively, and the recovered diol (+)-(R)-1.Alternatively, the same reaction sequence furnished the resolved diols (-)-(S)-1 and (+)-(R)-1 from (R,S)-1 and (+)-R-2, as well as optically pure 2,2'-bis(chloromethyl)-1,1'-binaphthyl (+)-(R)-5 from the racemic dibromide (R,S)-2 by using boron trichloride for ether cleavage.