37812-33-2 Usage
Uses
Used in Pharmaceutical Industry:
2-(Morpholin-4-ylmethyl)benzonitrile is used as an intermediate in the synthesis of various drugs and pharmaceuticals, contributing to the development of new medications and therapies.
Used in Organic Synthesis:
As a reagent in organic synthesis, 2-(Morpholin-4-ylmethyl)benzonitrile plays a crucial role in the creation of different chemical compounds, facilitating the advancement of chemical research and product development.
Used in Metal-Catalyzed Reactions:
2-(Morpholin-4-ylmethyl)benzonitrile is utilized as a ligand in metal-catalyzed reactions, enhancing the efficiency and selectivity of these processes, which are vital in various chemical transformations.
Used in Antitumor Research:
2-(MORPHOLIN-4-YLMETHYL)BENZONITRILE has been studied for its potential antiproliferative and antitumor properties, indicating its possible use in cancer research and the development of novel cancer treatments.
Overall, 2-(Morpholin-4-ylmethyl)benzonitrile is a multifaceted chemical with applications spanning across the pharmaceutical, chemical, and research industries, making it a valuable asset in the development of new products and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 37812-33-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,8,1 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 37812-33:
(7*3)+(6*7)+(5*8)+(4*1)+(3*2)+(2*3)+(1*3)=122
122 % 10 = 2
So 37812-33-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O/c13-9-11-3-1-2-4-12(11)10-14-5-7-15-8-6-14/h1-4H,5-8,10H2
37812-33-2Relevant academic research and scientific papers
Base-promoted N-alkylation using formamides as the N-sources in neat water
Chen, Wen-Xin,Zhang, Cai-Yun,Shao, Li-Xiong
, p. 880 - 885 (2014/01/23)
An efficient catalyst-free, alternative method for the C-N bond formation reaction of alkyl electrophiles using formamides as the N-sources was achieved under mild conditions. The reaction possesses the advantages of a broad range of substrates scope and wide functional group tolerance. It should also be noted that this process was performed using the environmentally benign water as the sole solvent, and high yield can also be achieved in ten-gram scale.
Highly efficient amination in neat water of benzyl chlorides with dialkylformamides catalysed by N-heterocyclic carbene-palladium(II)-1- methylimidazole complex
Chen, Wen-Xin,Zhang, Cai-Yun,Lu, Jian-Mei
, p. 611 - 614 (2013/11/06)
Dialkylformamides are excellent N-sources in the amination of benzyl chlorides when catalysed by a NHC-Pd(II)-Im complex. In the presence of NaOH and the catalyst, variously substituted benzyl chlorides and five different dialkylformamides reacted smoothly to afford the corresponding N,N-dialkyl-benzylamines in good to almost quantitative yields in eco-friendly solvent water at 50 °C within 3 h.
