37827-68-2

Usage

Uses

Used in Pharmaceutical Synthesis:
7-Hydroxy-2-tetralone is utilized as a key building block in the synthesis of various natural products and pharmaceuticals. Its unique structure allows it to serve as an intermediate in the creation of complex organic molecules, contributing to the development of new drugs and therapeutic agents.
Used in Research and Development:
In the research industry, 7-Hydroxy-2-tetralone is employed as a valuable compound for studying its biological activities. Its antioxidant and anti-inflammatory properties are of particular interest, as they may lead to the discovery of novel treatments for various diseases and conditions.
Used in Organic Compounds Synthesis:
7-Hydroxy-2-tetralone is also used as a precursor in the synthesis of a range of organic compounds. Its reactivity and functional groups make it a suitable candidate for the production of specialty chemicals and materials with specific properties and applications.

InChI:InChI=1/C10H10O2/c11-9-3-1-7-2-4-10(12)6-8(7)5-9/h1,3,5,11H,2,4,6H2

Upstream product

• 582-17-2 2,7-Dihydroxynaphthalene 
• 4133-34-0 7-methoxyl-2-tetralone 
• 108-98-5 thiophenol 
• 66628-99-7 3-(4-hydroxyphenyl)propanoyl chloride 
• 501-97-3 4-hydroxyphenylpropionic acid 
• 208932-51-8 3-(4-hydroxyphenyl)propionic acid allyl ester 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 

Downstream Products

• 84344-52-5 7-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-3,4-dihydro-1H-naphthalen-2-one 
• 1374428-94-0 (S)-1,2,3,4-tetrahydronaphthalene-2,7-diyl bis(4-bromobenzoate) 
• 41363-00-2 7-OH-AT 

Relevant academic research and scientific papers

Tetrahydroxynaphthalene reductase: Catalytic properties of an enzyme involved in reductive asymmetric naphthol dearomatization

In reduced circumstances: Tetrahydroxynaphthalene reductase shows a broad substrate range including alternate phenolic compounds and cyclic ketones. Structural modeling reveals major enzyme-substrate interactions; C-terminal truncation of the enzyme causes an altered substrate preference, in accordance with stabilization of the substrate by the C-terminal carboxylate (see picture). This effect allows the identification of a homologous enzyme. Copyright

6-SUBSTITUTED NICOTINAMIDE DERIVATIVES AS OPIOID RECEPTOR ANTAGONISTS

A compound of the formula (I) or a pharmaceutically acceptable salt, enantiomer, racemate, diastereomers or mixtures thereof, or a solvate thereof, formulations and methods of use thereof, as opioid receptor antagonists are disclosed wherein the variables are as described herein.

Efficient synthesis of resin-bound α-TMSdiazoketones and their use in solid-phase organic synthesis

α-TMSdiazoketones on a solid support could be simply and efficiently prepared by reaction of the corresponding resin-bound acid chlorides with excess TMSdiazomethane, without any bases. These α-TMSdiazoketones were used via carbenes or carbenoids for a variety of solid-phase reactions. These useful solid-phase reactions allow efficient construction of diverse compound libraries by use of combinatorial chemistry, due to the high reactivity and wide applications of the carbenes or carbenoids. (C) 2000 Elsevier Science Ltd.

Ionic hydrogenation of dihydroxynaphthalenes with cyclohexane in the presence of aluminum bromide

Reactions of 1,5-, 1,6-, 1,7-, 2,6-, and 2,7-dihydroxynaphthalenes with cyclohexane in the presence of excess aluminum bromide in methylene bromide quantitatively yield 5-, 6-, and 7-hydroxynaphthalen-1-ones and 6- and 7-hydroxynaphthalen-2-ones, respectively. Tricationic C-protonated complexes are presumed to be reactive intermediates in these processes.

HYDROXYLATION DU BENZALDEHYDE ET DE CETONES AROMATIQUES PAR LE PEROXYDE D'HYDROGENE EN MILIEU SUPERACIDE

Benzaldehyde and aromatic ketones are hydroxylated by hydrogen peroxide in SbF5-HF without formation of products arising from Baeyer-Villiger oxidation.