37832-33-0

Upstream product

• 626-19-7 Isophthalaldehyde 
• 77-78-1 dimethyl sulfate 
• 67-56-1 methanol 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 100501-45-9 3-(dimethoxymethyl)benzaldehyde 
• 164980-71-6 1-dimethoxymethyl-3-(1-hydroxyhexyl)benzene 
• 164980-99-8 methyl (5Z)-6-[3-(1-oxohexyl)phenyl]hex-5-enoate 
• 164980-74-9 (Z)-methyl 6-(3-(1-hydroxyhexyl)phenyl)hex-5-enoate 
• 164980-73-8 3-[1-(tert-butyl-diphenyl-silanyloxy)-hexyl]-benzaldehyde 
• 164980-72-7 tert-butyl-[1-(3-dimethoxymethyl-phenyl)-hexyloxy]-diphenyl-silane 
• 164980-89-6 6-{3-[1-(tert-butyl-diphenyl-silanyloxy)-hexyl]-phenyl}-hex-5-enoic acid methyl ester 
• 164980-58-9 2-(3-dimethoxymethyl-phenyl)-oxirane 
• 467216-99-5 3-(3-dimethoxymethyl-phenyl)-3-hydroxy-propionic acid ethyl ester 
• 164980-59-0 1-dimethoxymethyl-3-(1-hydroxynon-3-ynyl)benzene 
• 164981-01-5 (3-Dimethoxymethyl-phenyl)-[((Z)-4-pent-1-enyl)-phenyl]-methanol 
• 164981-03-7 3-[(tert-butyl-dimethyl-silanyloxy)-(4-pent-1-enyl-phenyl)-methyl]-benzaldehyde 
• 164980-68-1 1-[(1Z)-5-methoxycarbonylpent-1-enyl]-3-[(3Z)-1-hydroxynon-3-enyl]benzene 
• 467217-12-5 (Z)-6-[3-((3Z,6Z)-1-Hydroxy-nona-3,6-dienyl)-phenyl]-hex-5-enoic acid methyl ester 

Relevant academic research and scientific papers

Synthesis and antiaggregant properties of Stabilized analogues of polyunsaturated fatty acid metabolites

New aromatic and heteroaromatic analogues of polyunsaturated fatty acid metabolites have been prepared using short and versatile strategies. Preliminary studies of their activity as inhibitors of platelet aggregation are reported.

Synthesis of novel aromatic analogues of 12-HETE

New mono- and diaromatic analogues of the arachidonic acid metabolite 12-HETE have been prepared using versatile strategies. The easily accessible monoacetal of isophtalaldehyde 3 was developed as a key intermediate for these syntheses.

Efficient acetalisation of aldehydes catalyzed by titanium tetrachloride in a basic medium

The acetalisation of aliphatic and aromatic aldehydes is achieved in a basic medium by using catalytic amount of Ti(IV) chloride in MeOH in the presence of NH3 or Et3N. The present protocol shows many advantages over the well known base or acid catalysis: in fact, in contrast to base-promoted acetalisation, aldehydes with electron-rich carbonyl groups react easily, enolizable aldehydes do not undergo aldol condensation and, in contrast to acid-catalysis, migration of the double bond does not occur in the preparation of α,β-unsaturated acetals.