37849-85-7

Upstream product

• 104-51-8 1-butylbenzene 
• 584-48-5 2,4-dinitrobromobenzene 
• 85167-10-8 (s)-pinanediol butylboronate 
• 99-65-0 meta-dinitrobenzene 
• 109-72-8 n-butyllithium 
• 693-04-9 butyl magnesium bromide 
• 67-64-1 acetone 
• 7664-93-9 sulfuric acid 
• 63921-07-3 2,4-diamino-1-n-butylbenzene 

Downstream Products

• 63920-98-9 (E)-2-[5-((E)-1,2-Bis-methoxycarbonyl-vinylamino)-2-butyl-phenylamino]-but-2-enedioic acid dimethyl ester 

Relevant academic research and scientific papers

Alkylation of nitroaromatics with tetraalkylborate ion via electrochemical oxidation

Aromatic nucleophilic substitution reaction (SNAr) is one of the most thoroughly studied reactions. Alkylation of nitroaromatics with Grignard reagents via chemical oxidation of the σH-complexes is the most general method to introduc

Electrochemical synthesis of alkyl nitroaromatic compounds

Alkyl nitroaromatic compounds were readily prepared via nucleophilic aromatic substitution for hydrogen or a heteroatom by electrochemical oxidation of the a-complex. Butyllithium and butylmagnesium chloride were used as nucleophiles, and several nitrocompounds were tested to explore the possibilities of the NASH and NASX reactions promoted electrochemically.

Suzuki-Miyaura cross-coupling of lithium n-alkylborates

The palladium-catalyzed cross-coupling of lithium n-alkylborates, generated in situ via addition of sec-butyl lithium to boronate esters, proceeds in moderate to good yields with a wide variety of electrophiles.

Pharmaceutical compositions comprising pyridoquinoline derivatives and the use thereof

Pharmaceutical compositions comprising a 2,7-dicarboxy-4,9-dihydroxypyrido[2,3-g]quinoline derivative or a 2,8-dicarboxy-4,6-dihydroxypyrido[3,2-g]quinoline derivative. The compounds are active against syndromes or diseases initiated by an antigen-antibody reaction. Processes for the preparation of the compounds are also disclosed.