3787-10-8

Upstream product

• 670-96-2 2-Phenylimidazole 
• 2166-14-5 1,2,4,5-tetrazine-3,6-dicarboxylic acid dimethyl ester 
• 19209-60-0 N-acetyl iminostilbene 
• 91653-04-2 2-phenylsulfonyl-2-azabicyclo<3.3.1>non-6-ene 

Downstream Products

• 144563-93-9 2,7-Bis-(4-chloro-phenyl)-diiimidazo[1,5-b;1',5'-e][1,2,4,5]tetrazine-1,3,6,8-tetraone 
• 144563-91-7 2,7-Diphenyl-diiimidazo[1,5-b;1',5'-e][1,2,4,5]tetrazine-1,3,6,8-tetraone 
• 144564-07-8 7-(4-Chlorphenyl)2,6,7,8-tetrahydro-8-oxo-6-thioxoimidazo<1,5-b><1,2,4,5>tetrazin-3-carbonsaeuremethylester 
• 144563-96-2 2,7-Dicyclohexyl-diiimidazo[1,5-b;1',5'-e][1,2,4,5]tetrazine-1,3,6,8-tetraone 
• 2166-14-5 1,2,4,5-tetrazine-3,6-dicarboxylic acid dimethyl ester 
• 144563-95-1 2,7-Bis-(4-ethoxy-phenyl)-diiimidazo[1,5-b;1',5'-e][1,2,4,5]tetrazine-1,3,6,8-tetraone 
• 144563-92-8 2,7-Di-p-tolyl-diiimidazo[1,5-b;1',5'-e][1,2,4,5]tetrazine-1,3,6,8-tetraone 
• 144564-06-7 2,6,7,8-tetrahydro-8-oxo-7-phenyl-6-thioxoimidazo<1,5-b><1,2,4,5>tetrazin-3-carbonsaeuremethylester 
• 144564-05-6 2,7-diphenyl-1,6-dithioxo-1H,6H-diimidazo<1,5-b:1',5'-e><1,2,4,5>tetrazin-6,8(2H,7H)-dion 

Relevant academic research and scientific papers

Synthesis of N-substituted dibenzoazepine–pyridazine derivatives as potential neurologically active drugs

Syntheses of pyridazine derivatives of dibenzoazepine, starting from N-substituted-dibenzoazepines, are reported here for the first time. In the reaction sequence, N-substitute dibenzoazepine derivatives were synthesized and then, examined inverse electro

Dienophilicity of imidazole in inverse electron demand Diels-Alder reactions: Cycloadditions with 1,2,4,5-tetrazines and the structure of zarzissine

The inverse electron demand cycloadditions of 2-substituted imidazoles with dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate produced imidazo[4,5-d]pyridazines in good yields. This chemistry was applied to the synthesis of 2-amino-1H-imidazo[4,5-d]pyridazine (1), the structure reported for zarzissine, a cytotoxic marine alkaloid. Differences in the 1H- and 13C NMR spectra of 1 with those reported for zarzissine necessitated a structural revision, and zarzissine was then considered to be the corresponding 2-amino-1H-imidazo[4,5-b]pyrazine (2), which was subsequently synthesized from the parent heterocycle.