378741-99-2

Upstream product

• 378741-95-8 (E)-(S)-5-[(2R,4aR,6S,7R,8aS)-7-(tert-Butyl-dimethyl-silanyloxy)-4a,6-dimethyl-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl]-5-(4-methoxy-benzyloxy)-pent-2-enoic acid methyl ester 
• 378741-94-7 (S)-3-[(2R,4aR,6S,7R,8aS)-7-(tert-Butyl-dimethyl-silanyloxy)-4a,6-dimethyl-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl]-3-(4-methoxy-benzyloxy)-propan-1-ol 
• 378741-96-9 (E)-(S)-5-((2R,4aR,6R,7R,8aS)-7-Hydroxy-4a,6-dimethyl-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-5-(4-methoxy-benzyloxy)-pent-2-enoic acid methyl ester 
• 378741-97-0 [(2R,4aR,5S,7R,8aR,9aS,10aS)-5-(4-Methoxy-benzyloxy)-4a,10a-dimethyl-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl]-acetic acid methyl ester 
• 378741-98-1 (2R,4aR,5S,7S,8aR,9aS,10aS)-7-Allyl-5-(4-methoxy-benzyloxy)-4a,10a-dimethyl-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracene 
• 378742-10-0 (E)-3-[(2R,4aR,6S,7R,8aS)-7-(tert-Butyl-dimethyl-silanyloxy)-4a,6-dimethyl-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl]-acrylic acid ethyl ester 
• 378741-93-6 (S)-1-[(2R,4aR,6S,7R,8aS)-7-(tert-Butyl-dimethyl-silanyloxy)-4a,6-dimethyl-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl]-propane-1,3-diol 
• 378741-92-5 (E)-3-[(2R,4aR,6S,7R,8aS)-7-(tert-Butyl-dimethyl-silanyloxy)-4a,6-dimethyl-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl]-prop-2-en-1-ol 
• 374638-43-4 (2R,4aR,6R,7R,8aS)-7-(tert-Butyl-dimethyl-silanyloxy)-4a,6-dimethyl-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-6-carbaldehyde 
• 131311-03-0 tert-Butyl-((2R,4aR,6S,7R,8aS)-4a,6-dimethyl-2-phenyl-6-vinyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yloxy)-dimethyl-silane 
• 100-39-0 benzyl bromide 

Downstream Products

• 378742-00-8 (2R,4aR,5S,7S,8aR,9aS,10aS)-5-Benzyloxy-7-(3-benzyloxy-propyl)-4a,10a-dimethyl-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracene 
• 378742-05-3 (2R,3S,4aR,5S,7S,8aR,9aS,10aS)-5-Benzyloxy-7-(3-benzyloxy-propyl)-4a,10a-dimethyl-2-vinyl-decahydro-1,8,10-trioxa-anthracen-3-ol 
• 486394-94-9 (2S,3S,4aR,6S,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-(tert-butyl-dimethyl-silanyloxy)-2,8a-dimethyl-octahydro-pyrano[3,2-b]pyran-2-carbaldehyde 
• 378742-02-0 [(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-2,8a-dimethyl-2-vinyl-octahydro-pyrano[3,2-b]pyran-3-yloxy]-tert-butyl-dimethyl-silane 
• 494760-55-3 [(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-(tert-butyl-dimethyl-silanyloxy)-2,8a-dimethyl-octahydro-pyrano[3,2-b]pyran-2-yl]-acetaldehyde 
• 378742-01-9 [(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-(tert-butyl-dimethyl-silanyloxy)-2,8a-dimethyl-octahydro-pyrano[3,2-b]pyran-2-yl]-methanol 
• 494760-56-4 2-[(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-(tert-butyl-dimethyl-silanyloxy)-2,8a-dimethyl-octahydro-pyrano[3,2-b]pyran-2-yl]-ethanol 
• 378742-12-2 (E)-4-[(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-(tert-butyl-dimethyl-silanyloxy)-2,8a-dimethyl-octahydro-pyrano[3,2-b]pyran-2-yl]-but-2-en-1-ol 
• 378742-03-1 (E)-4-[(2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-(tert-butyl-dimethyl-silanyloxy)-2,8a-dimethyl-octahydro-pyrano[3,2-b]pyran-2-yl]-but-2-enoic acid ethyl ester 
• 378741-90-3 (3S,4aR,5S,7S,8aR,9aS,10aS)-5-Benzyloxy-7-(3-benzyloxy-propyl)-3-(4-methoxy-benzyloxy)-4a,10a-dimethyl-2-methylene-decahydro-1,8,10-trioxa-anthracene 
• 486394-93-8 (2S,3S,4aR,5S,7S,8aR,9aS,10aS)-5-Benzyloxy-7-(3-benzyloxy-propyl)-2-iodomethyl-3-(4-methoxy-benzyloxy)-4a,10a-dimethyl-decahydro-1,8,10-trioxa-anthracene 
• 378742-06-4 [(2R,3S,4aR,5S,7S,8aR,9aS,10aS)-5-Benzyloxy-7-(3-benzyloxy-propyl)-3-(4-methoxy-benzyloxy)-4a,10a-dimethyl-decahydro-1,8,10-trioxa-anthracen-2-yl]-methanol 
• 378742-07-5 C₆₁H₈₂O₁₃ 
• 378742-11-1 (2R,3S,4aR,6S,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-2-hydroxymethyl-2,8a-dimethyl-octahydro-pyrano[3,2-b]pyran-3-ol 

Relevant academic research and scientific papers

Total synthesis of (-)-gambierol

The first total synthesis of (-)-gambierol (1), a marine polycyclic ether toxin, has been achieved. Key features of the successful synthesis include (1) a convergent union of the ABC and EFGH ring fragments (5 and 6, respectively) via our developed B-alky

Synthetic studies toward gambierol. Convergent synthesis of the octacyclic polyether core.

[structure: see text]. A convergent synthetic route to the octacyclic polyether core of gambierol, a marine polycyclic ether toxin, has been developed. The synthesis involves construction of two fragments representing the ABC and EFGH ring systems followe