37901-87-4

Usage

Uses

Used in Pharmaceutical Industry:
2,3-DIAMINO-5-METHYLBENZOIC ACID is used as a precursor in the synthesis of various pharmaceuticals and organic compounds due to its versatile reactivity. It plays a crucial role in the development of new drugs and medicines.
Used in Chemical Industry:
2,3-DIAMINO-5-METHYLBENZOIC ACID is used as a building block in the production of dyes and pigments, contributing to the creation of a wide range of colorants for various applications.
Used in Industrial Processes:
2,3-DIAMINO-5-METHYLBENZOIC ACID is used as a corrosion inhibitor, helping to protect materials and equipment from degradation in various industrial processes.
Used in Anti-Tumor Research:
2,3-DIAMINO-5-METHYLBENZOIC ACID has been studied for its potential as an anti-tumor agent, with ongoing research exploring its effectiveness in combating cancer cells.
Used in Anti-Inflammatory Applications:
2,3-DIAMINO-5-METHYLBENZOIC ACID is also known for its anti-inflammatory properties, making it a potential candidate for the development of treatments for inflammatory conditions.

Upstream product

• 648934-53-6 2-[bis-(2,2,2-trifluoroacetyl)amino]-5-methylbenzoic acid 
• 573692-68-9 5-methyl-3-nitro-2-(2,2,2-trifluoroacetyl)aminobenzoic acid 
• 2941-78-8 2-Amino-5-methylbenzoic acid 
• 5465-34-9 2-amino-5-methyl-3-nitrobenzoic acid 

Downstream Products

• 124340-70-1 6-Methyl-2-phenyl-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-98-3 2-phenyl-6-methyl-1H-benzimidazole-4-carboxylic acid 

Relevant academic research and scientific papers

OXADIAZOLE DERIVATIVES AND PHARMACEUTICAL USES THEREOF

PROBLEM TO BE SOLVED: To provide therapeutic or preventive agents for various diseases or symptoms associated with a serotonin 4 receptor (particularly, neuropsychiatric diseases such as Alzheimer-type dementia). SOLUTION: The present invention provides a compound represented by formula (1) or a pharmaceutically acceptable salt thereof. In the formula (1), Het represents formula (Het-1) or the like, A represents formula (A-1) or the like, B represents (B-1) or the like, R1A represents a hydrogen atom, an alkyl group or the like, R2A, R5, R6 and R7 represent a hydrogen atom, a halogen atom, an alkyl group or the like, R8 and R9 represent a hydrogen atom, an alkyl group or the like, and l represents an integer of 0-4. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists

A series of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones (QXs) related to licostinel (Acea 1021) was synthesized and evaluated as antagonists for the glycine site of the N-methyl-D-asparate (NMDA) receptor. The in vitro potency of these

Potential Antitumor Agents. 59. Structure-Activity Relationships for 2-Phenylbenzimidazole-4-carboxamides, a New Class of "Minimal" DNA-Intercalating Agents Which May Not Act via Topoisomerase II

A series of substituted 2-phenylbenzimidazole-4-carboxamides has been synthesized and evaluated for in vitro and in vivo antitumor activity.These compounds represent the logical conclusion to our search for "minimal" DNA-intercalating agents with the lowest possible DNA-binding constants.Such "2-1" tricyclic chromophores, of lower aromaticity than the structurally similar 2-phenylquinolines, have the lowest DNA binding affinity yet seen in the broad series of tricyclic carboxamide intercalating agents.Despite very low in vitro cytotoxicities, several of the compoundshad moderate levels of in vivo antileukemic effects.However, the most interesting aspect of their biological activity was the lack of cross-resistance shown to an amsacrine-resistant P388 cell line, suggesting that these compounds may not express their cytotoxicity via interaction with topoisomerase II.