37909-65-2Relevant academic research and scientific papers
Quinine-catalyzed enantioselective michael addition of diphenyl phosphite to nitroolefins: Synthesis of chiral precursors of α-substituted β-aminophosphonates
Wang, Jian,Heikkinen, Lora D.,Li, Hao,Zu, Liansuo,Jiang, Wei,Xie, Hexin,Wang, Wei
, p. 1052 - 1056 (2007)
A quinine-promoted, enantioselective Michael addition reaction of diphenyl phosphite with nitroalkenes has been developed. This methodology affords a facile access to enantiomerically enriched β-nitrophosphates, precursors for the preparation of synthetic
New catalyst for phosphonylation of C=X electrophiles
Kolodiazhnyi, Oleg I.,Kolodiazhna, Olga O.
experimental part, p. 1637 - 1649 (2012/05/05)
Pyridinium perchlorate is found to be an efficient and recyclable catalyst for the reaction of trialkyl phosphites with various C=X electrophiles (aldehydes, ketones, ketophosphonates, imines, isocyanates, isothiocyanates, activated alkenes) to afford cor
Pyridinium perchlorate: A new catalyst for the reaction of trialkyl phosphites with the C=X electrophiles
Kolodyazhnaya,Kolodyazhnyi
scheme or table, p. 307 - 314 (2011/06/27)
Pyridinium perchlorate is an effective catalyst for the reaction of trialkyl phosphites with various C=X electrophiles: aldehydes, ketones, ketophosphonates, imines, isocyanates, isothiocyanates, and activated alkenes. The reaction leads to the formation
HClO4-SiO2 as a novel and recyclable catalyst for the phospha-michael addition of phosphorous nucleophiles to α,β- unsaturated malonates
Sobhani, Sara,Rezazadeh, Soodabeh
scheme or table, p. 1485 - 1488 (2010/08/22)
An efficient synthesis of β-phosphono malonates via phospha-Michael addition of phosphorous nucleophiles to α,β-unsaturated malonates in the presence of HClO4-SiO2 as a new and recyclable catalyst is described.
An efficient method for the phosphonation of C=X compounds
Kolodyazhnaya,Kolodyazhnaya,Kolodyazhnyi
experimental part, p. 709 - 722 (2011/01/08)
Reaction of trialkyl phosphites with C=X electrophiles (aldehydes, ketones, ketophosphonates, aldimines, ketimines, isocyanates, isothiocyanates, and activated olefins) in the presence of amines and anilines hydrohalides was studied. We found that pyridine hydrohalides effectively activate the reaction of tralkyl phosphites with various C=X electrophiles: aldehydes, ketones, ketophosphonates, aldimines, ketimines, isocyanates, isothiocyanates, and activated olefins. Particularly high activity showed pyridine hydroiodide. This reaction is a convenient method of synthesis of hydroxyphosphonates, aminophosphonates, carbamoylphosphonates, carbamoylthiophosphonates, and methylenebisphosphonates. Pleiades Publishing, Ltd., 2010.
Reactions of Ethyl phosphites with β-Nitrostyrenes. The Role of Nitrosoalkenes as Intermediates
Russell, Glen A.,Yao, Ching-Fa
, p. 6508 - 6513 (2007/10/02)
3-Phenyl-2-substituted-indoles are formed in high yields in the reaction of Ph2C=C(R)NO2 (R = H, Me, Ph) with (EtO)3P at 150 deg C while reaction with (EtO)2PO(1-)/(Et2O)P(O)H at room temperature forms the aziridines 1 with R = H, Me, Ph. 2,2-Diphenyl-3-substituted-2H-azirines formed by deoxygenation of the Michael-type aducts are postulated as intermediates.Reactions of PhCH=C(R)NO2 (R = H, Me, Ph) with (EtO)3P at 150 deg C or (EtO)2PO(1-)/(EtO)2P(O)H at room temperature give products resulting from the addition of the phosphorus nucleophile at the benzylidene carbonatom.Evidence for the formation of cyclic structures with pentacoordinated phosphorus atoms is presented for the reaction of Ph2C=C(Me)NO2 with (EtO)2PO(1-)/(EtO)2P(O)H and for PhCH=C(R)NO2 (R = H, Me, Ph) with (EtO)3P.The Michael-type adducts PhCHCH(R)NO2 (R = Me, Ph) undergo reaction upon treatment with aqueous base at 80-100 deg C followed by acidification to yield the 3-(diethoxyphosphinyl)-2-R-N-hydroxyindoles. 4-(Diethoxyphosphinyl)-3-R-4H-1,2-benzoxazines (13, R = Me, Ph) are formed by reaction with 85percent H2SO4 of the adducts of PhCH=C(R)NO2 with (EtO)2PO(1-) (R = Me) or (EtO)3P (R = Ph).
