379238-96-7

Basic information

• Product Name: C₁₃H₁₀N₂S₂
• Synonyms: C₁₃H₁₀N₂S₂
• CAS NO: 379238-96-7
• Molecular Weight: 258.368
• Mol File: 379238-96-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₀N₂S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₀N₂S₂(379238-96-7)
• EPA Substance Registry System: C₁₃H₁₀N₂S₂(379238-96-7)

Safety Data

• Hazardous Substances Data: 379238-96-7(Hazardous Substances Data)

Upstream product

• 35978-38-2 6-methyl-5-phenyl-3H-thieno[2,3-d]pyrimidin-4-one 
• 93-55-0 1-phenyl-propan-1-one 
• 4815-37-6 ethyl 2-amino-5-methyl-4-phenylthiophene-3-carboxylate 

Downstream Products

• 1175819-21-2 C₁₇H₁₆N₂O₂S₂ 
• 1018578-66-9 [(6-methyl-5-phenylthieno[2,3-d]pyrimidin-4-yl)thio]acetic acid 

Relevant articles and documents

Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin- 4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2

A novel series of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids has been synthesized and tested in vitro towards human protein kinase CK2. It was revealed that the most active compounds inhibiting CK2 are 3-{[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid and 3-{[5-(4-ethoxyphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid (IC 50 values are 0.1 μM and 0.125 μM, respectively). Structure-activity relationships of 28 tested thienopyrimidine derivatives have been studied and binding mode of this chemical class has been predicted. Evaluation of the inhibitors on seven protein kinases revealed considerable selectivity towards CK2.