379239-96-0Relevant academic research and scientific papers
Direct N-H/ N-Me Aziridination of Unactivated Olefins Using O-(Sulfonyl)hydroxylamines as Aminating Agents
Sabir, Shekh,Pandey, Chandra Bhan,Yadav, Ajay K.,Tiwari, Bhoopendra,Jat, Jawahar L.
, p. 12255 - 12260 (2018)
Unactivated aziridines are the core substructures in a plethora of bioactive natural products and serve as building blocks in organic synthesis. Despite this, very limited methods are available to access them directly from olefins, as most of the known me
Catalytic conversion of conjugated enones into optically active α-keto aziridines using chiral rare earth metal complexes
Sugihara, Hiroyasu,Daikai, Kazuhiro,Jin, Xiu Lan,Furuno, Hiroshi,Inanaga, Junji
, p. 2735 - 2739 (2007/10/03)
Optically active N-unsubstituted α-keto aziridines 2 were synthesized from conjugated enones 1 via the Sc[(R)-BNP]3-catalyzed enantioselective Michael addition of O-methylhydroxylamine followed by the La(O-i-Pr)3-catalyzed ring closu
