379269-22-4

Upstream product

• 379269-18-8 4-C-(hydroxymethyl)-1,2-O-isopropylidene-β-D-threo-pentofuranose 
• 379269-20-2 methyl 3,5-di-O-benzyl-4-C-[(benzyloxy)methyl]-α/β-D-threo-pentofuranoside 
• 379269-19-9 3,5-di-O-benzyl-4-C-[(benzyloxy)methyl]-1,2-O-isopropylidene-β-D-threo-pentofuranose 
• 379269-21-3 methyl 2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α/β-D-threo-pentofuranoside 

Downstream Products

• 934007-80-4 1-((2S,3S,4S)-3,4-Bis-benzyloxy-5,5-bis-benzyloxymethyl-tetrahydro-furan-2-yl)-4-hydroxy-1H-pyrimidin-2-one 
• 934007-75-7 1-((2R,3S,4S)-3,4-Bis-benzyloxy-5,5-bis-benzyloxymethyl-tetrahydro-furan-2-yl)-4-hydroxy-1H-pyrimidin-2-one 
• 934007-80-4 1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α-D-threo-pentofuranosyl}uracil 
• 934007-75-7 1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-β-D-threo-pentofuranosyl}uracil 
• 379269-24-6 1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α-D-threo-pentofuranosyl}thymine 
• 934007-76-8 1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-β-D-threo-pentofuranosyl}thymine 
• 934007-82-6 5-fluoro-1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α-D-threo-pentofuranosyl}uracil 
• 934007-78-0 5-fluoro-1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-β-D-threo-pentofuranosyl}uracil 
• 934007-87-1 6-chloro-7-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-D-threo-pentofuranosyl}purine 
• 934007-88-2 6-chloro-9-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-β-D-threo-pentofuranosyl}purine 
• 934007-89-3 6-chloro-9-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α-D-threo-pentofuranosyl}purine 
• 934007-90-6 9-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-β-D-threo-pentofuranosyl}adenine 
• 934007-91-7 9-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α-D-threo-pentofuranosyl}adenine 
• 934007-85-9 1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α-D-threo-pentofuranosyl}cytosine 

Relevant academic research and scientific papers

Synthesis and antiproliferative activity of some 4′-C-hydroxymethyl α- and -β-D-arabino-pentofuranosyl pyrimidine nucleosides

A suitably protected 4-C-hydroxymethyl-arabino-pentofuranose was prepared and condensed with the following nucleobases: uracil, 5-fluorouracil and thymine. The corresponding cytosine and 5-fluorocytosine derivatives have also been obtained respectively from the uracil and 5-fluorouracil nucleosides. Separation of the anomeric mixtures followed by deprotection afforded the target compounds that were found to be non-cytotoxic to CCRF-CEM leukemia cells.