379269-20-2

Upstream product

• 67-56-1 methanol 
• 379269-18-8 4-C-(hydroxymethyl)-1,2-O-isopropylidene-β-D-threo-pentofuranose 
• 379269-19-9 3,5-di-O-benzyl-4-C-[(benzyloxy)methyl]-1,2-O-isopropylidene-β-D-threo-pentofuranose 

Downstream Products

• 379269-21-3 methyl 2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α/β-D-threo-pentofuranoside 
• 934007-78-0 1-((2R,3S,4S)-3,4-Bis-benzyloxy-5,5-bis-benzyloxymethyl-tetrahydro-furan-2-yl)-5-fluoro-4-hydroxy-1H-pyrimidin-2-one 
• 934007-82-6 1-((2S,3S,4S)-3,4-Bis-benzyloxy-5,5-bis-benzyloxymethyl-tetrahydro-furan-2-yl)-5-fluoro-4-hydroxy-1H-pyrimidin-2-one 
• 934007-84-8 5-fluoro-1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-β-D-threo-pentofuranosyl}cytosine 
• 934007-86-0 5-fluoro-1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α-D-threo-pentofuranosyl}cytosine 
• 934007-76-8 1-((2R,3S,4S)-3,4-Bis-benzyloxy-5,5-bis-benzyloxymethyl-tetrahydro-furan-2-yl)-4-hydroxy-5-methyl-1H-pyrimidin-2-one 
• 379269-24-6 1-((2S,3S,4S)-3,4-Bis-benzyloxy-5,5-bis-benzyloxymethyl-tetrahydro-furan-2-yl)-4-hydroxy-5-methyl-1H-pyrimidin-2-one 
• 934007-83-7 1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-β-D-threo-pentofuranosyl}cytosine 
• 934007-85-9 1-{2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α-D-threo-pentofuranosyl}cytosine 
• 934007-75-7 1-((2R,3S,4S)-3,4-Bis-benzyloxy-5,5-bis-benzyloxymethyl-tetrahydro-furan-2-yl)-4-hydroxy-1H-pyrimidin-2-one 
• 934007-80-4 1-((2S,3S,4S)-3,4-Bis-benzyloxy-5,5-bis-benzyloxymethyl-tetrahydro-furan-2-yl)-4-hydroxy-1H-pyrimidin-2-one 
• 379269-22-4 1-O-acetyl-2,3,5-tri-O-benzyl-4-C-[(benzyloxy)methyl]-α/β-D-threo-pentofuranose 

Relevant academic research and scientific papers

Synthesis and antiproliferative activity of some 4′-C-hydroxymethyl α- and -β-D-arabino-pentofuranosyl pyrimidine nucleosides

A suitably protected 4-C-hydroxymethyl-arabino-pentofuranose was prepared and condensed with the following nucleobases: uracil, 5-fluorouracil and thymine. The corresponding cytosine and 5-fluorocytosine derivatives have also been obtained respectively from the uracil and 5-fluorouracil nucleosides. Separation of the anomeric mixtures followed by deprotection afforded the target compounds that were found to be non-cytotoxic to CCRF-CEM leukemia cells.