37944-73-3Relevant academic research and scientific papers
Microwave assisted synthesis of 1,5-disubstituted hydantoins and thiohydantoins in solvent-free conditions
Paul,Gupta,Gupta,Loupy
, p. 75 - 78 (2007/10/03)
1,5-Disubstituted hydantoins/thiohydantoins 3a-p have been synthesized in 81-95% yield by a microwave-promoted solvent-free condensation of arylglyoxals 1 and phenylurea/thiourea 2 using PPE as a reaction mediator. This method can be extended towards the parallel synthesis of 3. The workup is simple and involves treatment with ice-cold water.
Synthesis of 5-membered ring-type compounds as potential cholecystokinin receptor ligands
Pentassuglia,Luca Araldi,Donati,Feriani,Oliosi,Pasquarello,Ursini
, p. 573 - 581 (2007/10/03)
Imidazolidine-2,4-diones and 1,5-diphenyl tetrainic acid derivatives were selected in order to evaluate some 5-membered heterocyclic ring compounds as potential templates for the synthesis of CCK receptor ligands. All the compounds were evaluated in vitro towards both CCK-B and CCK-A receptors.
