380223-64-3

Basic information

• Product Name: (R)-2-(5-Bromo-2-methoxy-benzoylamino)-3-hydroxy-propionic acid methyl ester
• Synonyms: (R)-2-(5-Bromo-2-methoxy-benzoylamino)-3-hydroxy-propionic acid methyl ester
• CAS NO: 380223-64-3
• Molecular Weight: 332.151
• Mol File: 380223-64-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-(5-Bromo-2-methoxy-benzoylamino)-3-hydroxy-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-(5-Bromo-2-methoxy-benzoylamino)-3-hydroxy-propionic acid methyl ester(380223-64-3)
• EPA Substance Registry System: (R)-2-(5-Bromo-2-methoxy-benzoylamino)-3-hydroxy-propionic acid methyl ester(380223-64-3)

Safety Data

• Hazardous Substances Data: 380223-64-3(Hazardous Substances Data)

Upstream product

• 2476-35-9 5-bromo-2-methoxybenzoic acid 
• 62910-63-8 5-bromo-2-methoxybenzoyl chloride 
• 5874-57-7 R-(-)-serine methyl ester hydrochloride 

Downstream Products

• 380223-67-6 (R)-2-(5-Bromo-2-methoxy-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 380223-71-2 Methanesulfonic acid (R)-2-(5-bromo-2-methoxy-phenyl)-4,5-dihydro-oxazol-4-ylmethyl ester 
• 380223-69-8 [(S)-2-(5-Bromo-2-methoxy-phenyl)-4,5-dihydro-oxazol-4-yl]-methanol 

Relevant articles and documents

Benzamide bioisosteres incorporating dihydroheteroazole substructures: EPC synthesis and SAR leading to a selective dopamine D4 receptor partial agonist (FAUC 179)

Conformationally restricted benzamide bioisosteres were investigated when the chiral phenyldihydroimidazole derivative 4e (FAUC 179) showed strong and highly selective dopamine D4 receptor binding (Kihigh = 0.95 nM). Mitogenesis experiments indicated partial agonist properties (42%). EPC syntheses of the target compounds of type 4 were performed starting from α-amino acids.