380501-40-6

Basic information

• Product Name: 5-hydroxy-7-methoxy-2-phenyl-4-quinolone
• Synonyms: 5-hydroxy-7-methoxy-2-phenyl-4-quinolone
• CAS NO: 380501-40-6
• Molecular Weight: 267.284
• Mol File: 380501-40-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-7-methoxy-2-phenyl-4-quinolone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-7-methoxy-2-phenyl-4-quinolone(380501-40-6)
• EPA Substance Registry System: 5-hydroxy-7-methoxy-2-phenyl-4-quinolone(380501-40-6)

Safety Data

• Hazardous Substances Data: 380501-40-6(Hazardous Substances Data)

Upstream product

• 829-20-9 2',4'-dimethoxyacetophenone 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 98-88-4 benzoyl chloride 
• 94088-74-1 N-(3,5-dimethoxyphenyl)benzamide 
• 159188-33-7 5,7-dimethoxy-2-phenylquinoline-4(1H)-one 
• 10272-07-8 3.5-dimethoxyaniline 
• 380501-39-3 N-(2-acetyl-3,5-dimethoxy-phenyl)-benzamide 

Relevant articles and documents

Alkylation of 2-phenyl-4-quinolones: Synthetic and structural studies

The alkylation Of 2-phenyl-4-quinolones was investigated and showed that the N-alkylation versus O-alkylation is highly dependent on whether C-5 is hydroxylated or not. N-Alkylation is favoured by the presence of a 5-hydroxyl group. The synthetic and the NMR structural studies are reported.

Antimitotic activity of 5-hydroxy-7-methoxy-2-phenyl-4-quinolones

We report the synthesis of 5-hydroxy-7-methoxy-2-phenyl-4-quinolones and their biological activity as antitumor agents. These molecules were initially evaluated for their ability to induce cell cycle arrest in the G2/M phase. Compounds that showed signifi