38070-73-4

Usage

Uses

Used in Pharmaceutical Industry:
4-Hydroxymethyl-3-methylpyridine is used as an intermediate in organic synthesis for producing pharmaceuticals. Its unique structure allows it to be a building block in the development of various drugs, contributing to the creation of new medicinal compounds with potential therapeutic applications.
Used in Pesticide Industry:
In the pesticide industry, 4-Hydroxymethyl-3-methylpyridine serves as an intermediate in the synthesis of various pesticides. Its chemical properties make it suitable for the production of compounds that can effectively control and manage pests, thereby enhancing crop protection and yield.
Used in Polymer Production:
4-Hydroxymethyl-3-methylpyridine is also used as a building block in the production of polymers. Its structural features enable it to be incorporated into polymer chains, potentially improving the properties of the resulting polymers, such as their stability, strength, or other desirable characteristics.

InChI:InChI=1/C7H9NO/c1-6-4-8-3-2-7(6)5-9/h2-4,9H,5H2,1H3

Upstream product

• 58997-11-8 3-methylisonicotinic acid ethyl ester 
• 116985-92-3 Methyl 3-methylpyridine-4-carboxylate 
• 4021-12-9 3-methyl-isonicotinic acid 
• 583-58-4 3,4-Lutidin 

Relevant academic research and scientific papers

Positive electron medicine [18F] FPMMP as well as preparation method and midbody thereof

The invention relates to a positive electron medicine [18F] FPMMP as well as a preparation method and a midbody thereof. The positive electron medicine [18F] FPMMP has a following structure shown in the description. The positive electron medicine [18F] FPMMP can reach the peak value after 10 minutes after the injection to the brain part of the non-human primate animals; the clinic use is convenient; the BPND can reach 2.14 in a cingulate cortex.

Spin-Center Shift-Enabled Direct Enantioselective α-Benzylation of Aldehydes with Alcohols

Nature routinely engages alcohols as leaving groups, as DNA biosynthesis relies on the removal of water from ribonucleoside diphosphates by a radical-mediated "spin-center shift" (SCS) mechanism. Alcohols, however, remain underused as alkylating agents in synthetic chemistry due to their low reactivity in two-electron pathways. We report herein an enantioselective α-benzylation of aldehydes using alcohols as alkylating agents based on the mechanistic principle of spin-center shift. This strategy harnesses the dual activation modes of photoredox and organocatalysis, engaging the alcohol by SCS and capturing the resulting benzylic radical with a catalytically generated enamine. Mechanistic studies provide evidence for SCS as a key elementary step, identify the origins of competing reactions, and enable improvements in chemoselectivity by rational photocatalyst design.

Therapeutic Agents 812

A compound of formula I or a pharmaceutically acceptable salt thereof, processes for preparing such compounds, their use as GPR119 modulators, methods for their therapeutic use, particularly in the treatment of obesity and diabetes mellitus, and pharmaceutical compositions containing them.

Oxidation of methyl heteroaryls with molecular oxygen: A facile synthesis of 2-[N-(tert-butoxycarbonyl)amino]-4-pyridinecarbaldehyde

Oxidation of nitrogen-based methyl heteroaryls with molecular oxygen resulted in the formation of the corresponding benzyl alcohols. While experimentally easy and amenable to large-scale preparations, this approach has limitations with respect to the particular nature of heterocyclic substrates. Using this methodology, the title compound, 2-[N-(tert-butoxycarbonyl)amino]-4- pyridinecarbaldehyde, considered to be a versatile pharmaceutical intermediate, was prepared on a multigram scale. Georg Thieme Verlag Stuttgart.

Carbapenem antibiotics

Disclosed are novel carbapenem derivatives characterized by a 2-substituent of the formula STR1 in which A represents a C1 -C6 straight or branched chain alkylene group; R5 represents an optionally substituted aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, aryl, araliphatic, heteroaryl, heteroaraliphatic, heterocyclyl or heterocyclyl-aliphatic radial and STR2 represents a nitrogen-containing aromatic heterocycle attached to the alkylene group A at a ring carbon atom and quaternized by substituent R5. Such derivatives are useful as potent antibacterial agents.