380860-70-8

Basic information

• Product Name: 3-(5-fluoro-2-iodo-phenoxy)-3,6-dihydro-2H-pyridine-1-carboxylic acid ethyl ester
• CAS NO: 380860-70-8
• Molecular Weight: 391.181
• Mol File: 380860-70-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(5-fluoro-2-iodo-phenoxy)-3,6-dihydro-2H-pyridine-1-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-fluoro-2-iodo-phenoxy)-3,6-dihydro-2H-pyridine-1-carboxylic acid ethyl ester(380860-70-8)
• EPA Substance Registry System: 3-(5-fluoro-2-iodo-phenoxy)-3,6-dihydro-2H-pyridine-1-carboxylic acid ethyl ester(380860-70-8)

Safety Data

• Hazardous Substances Data: 380860-70-8(Hazardous Substances Data)

Upstream product

• 1037831-19-8 4-fluoro-1-iodo-2-methoxymethoxy-benzene 
• 126940-10-1 1-fluoro-3-(methoxy-methoxy)benzene 
• 372-20-3 3-fluorophenol 
• 186589-87-7 5-fluoro-2-iodo-phenol 

Relevant articles and documents

Synthesis of constrained arylpiperidines using intramolecular Heck or radical reactions

Two intramolecular routes were experimented to reach the hexahydrobenzofuro[2,3-c]pyridine platform: a Heck and a radical reaction. The radical route was applicable to all substrates, whereas the Heck route was of limited use. The key adducts were obtained via a Mitsunobu condensation between halogenated phenols and an allylic alcohol, the 3-hydroxy-tetrahydropyridine.