380909-09-1Relevant articles and documents
Identification of a series of oxadiazole-substituted α-isopropoxy phenylpropanoic acids with activity on PPARα, PPARγ, and PPARδ
Liu, Kevin G,Smith, Jennifer S,Ayscue, Andrea H,Henke, Brad R,Lambert, Millard H,Leesnitzer, Lisa M,Plunket, Kelli D,Willson, Timothy M,Sternbach, Daniel D
, p. 2385 - 2388 (2007/10/03)
A series of oxadiazole-substituted α-isopropoxy phenylpropanoic acids with dual agonist activity on PPARα and PPARγ is described. Several of these compounds also showed partial agonist activity on PPARδ. Resolution of one analogue showed that PPARα and PP