38107-10-7

Basic information

• Product Name: (4-PHENYL-THIAZOL-2-YL)-ACETIC ACID
• Synonyms: (4-PHENYL-THIAZOL-2-YL)-ACETIC ACID;RARECHEM AL BO 0890;2-(4-phenylthiazol-2-yl)acetic acid;4-Phenyl-2-thiazoleacetic acid;(4-Phenyl-1,3-thiazol-2-yl)acetic acid;4-phenylthiazole-2-ylacetic acid
• CAS NO: 38107-10-7
• Molecular Formula: C₁₁H₉NO₂S
• Molecular Weight: 219.26
• Mol File: 38107-10-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 90-91℃
• Boiling Point: 423 °C at 760 mmHg
• Flash Point: 209.6 °C
• Appearance: /
• Density: 1.329
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (4-PHENYL-THIAZOL-2-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (4-PHENYL-THIAZOL-2-YL)-ACETIC ACID(38107-10-7)
• EPA Substance Registry System: (4-PHENYL-THIAZOL-2-YL)-ACETIC ACID(38107-10-7)

Safety Data

• Hazardous Substances Data: 38107-10-7(Hazardous Substances Data)

Usage

Uses

4-Phenyl-2-thiazoleacetic Acid is a reactant used to prepare heterocyclic acetamide and benzamide derivatives as β3-adrenergic receptor agonists.

Upstream product

• 1826-23-9 2-chloro-4-phenylthiazole 
• 41381-89-9 2-(4-phenylthiazol-2-yl)acetonitrile 
• 2010-06-2 2-Amino-4-phenylthiazole 
• 6094-68-4 5-phenyl-2,3-dihydro-thiazolo[2,3-b]thiazolylium; bromide 
• 70-11-1 α-bromoacetophenone 
• 171360-72-8 methoxycarbonyl(4-phenylthiazole-2-yl)-methylenetriphenylphosphorane 
• 339561-18-1 3-oxo-2-(4-phenyl-thiazol-2-yl)-butyric acid ethyl ester 

Downstream Products

• 1221931-52-7 C₂₃H₂₄N₂O₃S 
• 1221918-42-8 C₁₉H₁₆N₂O₃S 

Relevant articles and documents

ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON VASCULAR ENDOTHELIAL LIPASE

Disclosed is a compound which is useful as an endothelial lipase inhibitor. A pharmaceutical composition having inhibitory activity on endothelial lipase comprising a compound represented by the formula: , its pharmaceutically acceptable salt, or a solvate thereof, wherein Ring A is nitrogen-containing hetero ring, Ring A may be substituted with a substituent other than a group represented by the formula: -C(R1R2)-C(=O)-NR3R4 and a group represented by the formula: -R5, a broken line represents the presence or the absence of a bond, Z is -NR6-, =N-, -O-, or -S-, R6 is halogen, substituted or unsubstituted alkyl or the like, R1 and R2 are each independently hydrogen, halogen, hydroxy, cyano, nitro, carboxy or substituted or unsubstituted alkyl, R3 is hydrogen or substituted or unsubstituted alkyl, R4 is hydrogen, substituted or unsubstituted alkyl or the like, R3 and R4 taken together with the adjacent nitrogen atom to which they are attached may form a substituted or unsubstituted ring, R5 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl or the like.

Studies of heterocyclic compounds. VII. The reactions of 5,6 dihydrothiazolo [2,3 b]thiazolium salts with carbanions

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