1826-23-9

Basic information

• Product Name: 2-Chloro-4-phenylthiazole
• Synonyms: 2-CHLORO-4-PHENYLTHIAZOLE;2-CHLORO-4-PHENYL-1,3-THIAZOLE;Thiazole, 2-chloro-4-phenyl-;2-Chloro-4-phenylthiazole 97%;2-Chloro-4-phenyl-thiazaole, 97%
• CAS NO: 1826-23-9
• Molecular Formula: C₉H₆ClNS
• Molecular Weight: 195.67
• Product Categories: Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Thiazoles;ThiazolesHeterocyclic Building Blocks
• Mol File: 1826-23-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 47-50°C
• Boiling Point: 338.3°C at 760 mmHg
• Flash Point: 110 °C
• Appearance: /
• Density: 1.309g/cm³
• Vapor Pressure: 0.000194mmHg at 25°C
• Refractive Index: 1.616
• CAS DataBase Reference: 2-Chloro-4-phenylthiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4-phenylthiazole(1826-23-9)
• EPA Substance Registry System: 2-Chloro-4-phenylthiazole(1826-23-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 1826-23-9(Hazardous Substances Data)

Usage

General Description

2-Chloro-4-phenylthiazole is a chemical compound with the molecular formula C9H6ClNS. It is a thiazole derivative that contains a chlorine atom and a phenyl group attached to the thiazole ring. 2-Chloro-4-phenylthiazole is mainly used in the synthesis of various pharmaceuticals and agricultural chemicals. It has been studied for its potential antifungal, antibacterial, and anti-inflammatory properties. 2-Chloro-4-phenylthiazole may also have applications in the development of new materials and chemical processes. As with any chemical compound, proper safety precautions should be taken when handling and working with 2-Chloro-4-phenylthiazole to minimize potential health hazards.

InChI:InChI=1/C9H6ClNS/c10-9-11-8(6-12-9)7-4-2-1-3-5-7/h1-6H

Upstream product

• 3884-31-9 4-phenyl-3H-1,3-thiazol-2-one 
• 2010-06-2 2-Amino-4-phenylthiazole 
• 5399-30-4 2-oxo-2-phenylethylthiocyanate 

Downstream Products

• 129865-55-0 4-phenyl-2-(pyrrolidin-1-yl)thiazole-5-carbaldehyde 
• 65358-80-7 4-phenyl-2-(piperidin-1-yl)thiazole-5-carbaldehyde 
• 129880-85-9 2-(morpholin-4-yl)-4-phenylthiazole-5-carbaldehyde 
• 52963-23-2 3-Phenyl-6,7,8,9-tetrahydro<1>benzothieno<2,3-d>thiazolo<3,2-a>pyrimidin-5(H)-one 
• 80553-55-5 1-(4-Phenyl-2-thiazolyl)-3-pyrazolidinone 
• 2740-95-6 1,3-dimethyl-1-phenyl-thiourea 
• 77627-63-5 2-N-(β-hydroxyethylamino)-4-phenylthiazole 
• 50379-23-2 2-dimethylamino-4-phenylthiazole-5-carbaldehyde 
• 129865-60-7 2-chloro-4-phenylthiazole-5-carbaldehyde 
• 77627-64-6 2-N-(β-chloroethylamino)-4-phenylthiazole 
• 77627-66-8 N-<2-(4'-phenylthiazol-2'-ylamino)ethyl>-N'-phenylpiperazine 
• 77627-65-7 N-<2-(4'-phenylthiazol-2'-ylamino)ethyl>-N'-(o-tolyl)piperazine 
• 1826-12-6 4-phenyl-thiazole 
• 1826-16-0 2-methyl-4-phenylthiazole 

Relevant articles and documents

ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON VASCULAR ENDOTHELIAL LIPASE

Disclosed is a compound which is useful as an endothelial lipase inhibitor. A pharmaceutical composition having inhibitory activity on endothelial lipase comprising a compound represented by the formula: , its pharmaceutically acceptable salt, or a solvate thereof, wherein Ring A is nitrogen-containing hetero ring, Ring A may be substituted with a substituent other than a group represented by the formula: -C(R1R2)-C(=O)-NR3R4 and a group represented by the formula: -R5, a broken line represents the presence or the absence of a bond, Z is -NR6-, =N-, -O-, or -S-, R6 is halogen, substituted or unsubstituted alkyl or the like, R1 and R2 are each independently hydrogen, halogen, hydroxy, cyano, nitro, carboxy or substituted or unsubstituted alkyl, R3 is hydrogen or substituted or unsubstituted alkyl, R4 is hydrogen, substituted or unsubstituted alkyl or the like, R3 and R4 taken together with the adjacent nitrogen atom to which they are attached may form a substituted or unsubstituted ring, R5 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl or the like.

REACTIONS WITH HETEROCYCLIC DIAZONIUM SALTS: SYNTHESIS OF SEVERAL NEW THIAZOLOAS-TRIAZINES AND THIAZOLO1,2,4-TRIAZOLE DERIVATIVES

Several new stable thiazoloas-triazines could be synthesized via coupling of diazotized aminothiazole with active nitrile reagents.On the other hand, several new thiazolyl hydrazonyl chlorides and thiazolyl pyridazine could be synthesized via coupl