1826-23-9

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Chloro-4-phenylthiazole is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs with potential therapeutic benefits.
Used in Agricultural Chemical Synthesis:
2-Chloro-4-phenylthiazole also serves as a precursor in the production of agricultural chemicals, where it can be incorporated into formulations to enhance crop protection and yield.
Used in Antifungal Applications:
2-Chloro-4-phenylthiazole is studied for its potential antifungal properties, making it a candidate for use in treatments and products aimed at controlling fungal infections in various settings.
Used in Antibacterial Applications:
2-Chloro-4-phenylthiazole has also been investigated for its antibacterial capabilities, suggesting its potential use in combating bacterial infections and contributing to public health and sanitation.
Used in Anti-inflammatory Applications:
Research into the anti-inflammatory properties of 2-Chloro-4-phenylthiazole indicates its possible use in the development of anti-inflammatory medications, which could help manage inflammation-related conditions.
Used in Material Science and Chemical Processes:
2-Chloro-4-phenylthiazole may also find applications in the development of new materials and chemical processes, where its unique chemical structure can contribute to innovative solutions and advancements in various industries.

InChI:InChI=1/C9H6ClNS/c10-9-11-8(6-12-9)7-4-2-1-3-5-7/h1-6H

Upstream product

• 3884-31-9 4-phenyl-3H-1,3-thiazol-2-one 
• 5399-30-4 2-oxo-2-phenylethylthiocyanate 
• 2010-06-2 2-Amino-4-phenylthiazole 

Downstream Products

• 59439-65-5 3-(2-chloro-phenyl)-2-imino-4-(4-phenyl-thiazol-2-ylamino)-2,3-dihydro-thiazole-5-carboxylic acid ethyl ester 
• 79576-71-9 4,4'-diphenyl-2,2'-sulfanediyl-bis-thiazole 
• 2103-88-0 2-Mercapto-4-phenylthiazole 
• 19688-14-3 2-chloro-5-nitro-4-phenyl-thiazole 
• 34176-52-8 2-hydrazino-4-phenylthiazole 
• 122320-82-5 2-[Methyl-(4-phenyl-thiazol-2-yl)-amino]-ethanol 
• 52881-22-8 6,7-dimethyl-3-phenyl-5H-thiazolo <3,2-a> thieno <2,3-d> pyrimidine-5-one 
• 68194-87-6 4-(4'-Phenyl-3'-methyl-Δ⁴'-thiazoline-2'-imino)phenylacetic acid 
• 61323-72-6 4,5-Dihydro-7-phenylthiazolo<2,3-c><1,2,4>triazepin-3(2H)-one 
• 61323-66-8 3-Chloropropanoic acid 2-(4-phenyl-2-thiazolyl)hydrazide 
• 960312-68-9 C₂₄H₃₁N₃S 
• 1826-12-6 4-phenyl-thiazole 
• 1826-16-0 2-methyl-4-phenylthiazole 
• 1221918-42-8 C₁₉H₁₆N₂O₃S 

Relevant academic research and scientific papers

ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON VASCULAR ENDOTHELIAL LIPASE

Disclosed is a compound which is useful as an endothelial lipase inhibitor. A pharmaceutical composition having inhibitory activity on endothelial lipase comprising a compound represented by the formula: , its pharmaceutically acceptable salt, or a solvate thereof, wherein Ring A is nitrogen-containing hetero ring, Ring A may be substituted with a substituent other than a group represented by the formula: -C(R1R2)-C(=O)-NR3R4 and a group represented by the formula: -R5, a broken line represents the presence or the absence of a bond, Z is -NR6-, =N-, -O-, or -S-, R6 is halogen, substituted or unsubstituted alkyl or the like, R1 and R2 are each independently hydrogen, halogen, hydroxy, cyano, nitro, carboxy or substituted or unsubstituted alkyl, R3 is hydrogen or substituted or unsubstituted alkyl, R4 is hydrogen, substituted or unsubstituted alkyl or the like, R3 and R4 taken together with the adjacent nitrogen atom to which they are attached may form a substituted or unsubstituted ring, R5 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl or the like.

CYCLIC INHIBITORS OF 11β-HYDROXYSTERIOD DEHYDROGENASE 1

This invention relates to novel compounds of the Formula (I), (Ia), (Ib), (Ic), (Id), (Ie), (If), (Ig), (Ih); (Ii); (Ij), (Ik), (II) pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11 β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of cortisol in a cell or the inhibition of the conversion of cortisone to cortisol in a cell.

REACTIONS WITH HETEROCYCLIC DIAZONIUM SALTS: SYNTHESIS OF SEVERAL NEW THIAZOLOAS-TRIAZINES AND THIAZOLO1,2,4-TRIAZOLE DERIVATIVES

Several new stable thiazoloas-triazines could be synthesized via coupling of diazotized aminothiazole with active nitrile reagents.On the other hand, several new thiazolyl hydrazonyl chlorides and thiazolyl pyridazine could be synthesized via coupl