3811-49-2

Basic information

• Product Name: SALITHION
• Synonyms: o-methylcyclico,o-(methylene-o-phenylene)phosphorothioate;Phosphorothioic acid, cyclic O,O-(methylene-o-phenylene) O-methyl ester;Phosphorothioic acid, O-methyl ester, cyclic O,O-ester with o-hydroxybenzyl alcohol;phosphorothioicacid,cyclico,o-(methylene-o-phenylene)o-methylester;phosphorothioicacid,o-methylester,cyclico,o-esterwitho-hydroxybenzylalcohol;Saligenin cyclic methyl phosphorothionate;saligenincyclicmethylphosphorothionate;Salithion-sumitomo
• CAS NO: 3811-49-2
• Molecular Formula: C₈H₉O₃PS
• Molecular Weight: 216.19
• EINECS: 223-292-3
• Mol File: 3811-49-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 55-56℃ (methanol )
• Boiling Point: 274.4°Cat760mmHg
• Flash Point: 119.8°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 0.00907mmHg at 25°C
• Refractive Index: 1.59
• Storage Temp.: 0-6°C
• Water Solubility: 43 mg l-1
• BRN: 1875270
• CAS DataBase Reference: SALITHION(CAS DataBase Reference)
• NIST Chemistry Reference: SALITHION(3811-49-2)
• EPA Substance Registry System: SALITHION(3811-49-2)

Safety Data

• Hazard Codes: T,N
• Statements: 24/25-39/25-51/53
• Safety Statements: 36/37-38-45-61
• RIDADR: 2783
• WGK Germany: 3
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 3811-49-2(Hazardous Substances Data)

Usage

General Description

SALITHION is a chemical compound that is commonly used as an insecticide and acaricide. Its active ingredient is known as monocrotophos, which acts as a cholinesterase inhibitor, causing paralysis and ultimately death in targeted pests. It is mainly used in agricultural settings to control a variety of insect and mite pests on crops such as cotton, rice, and vegetables. However, due to its high toxicity to humans and non-target organisms, SALITHION has been banned or restricted in many countries and its use is heavily regulated. Proper handling and application of SALITHION are essential to minimize its impact on the environment and human health.

InChI:InChI=1/C8H9O3PS/c1-9-12(13)10-6-7-4-2-3-5-8(7)11-12/h2-5H,6H2,1H3

Upstream product

• 90-01-7 salicylic alcohol 
• 343628-27-3 O-methyl-O-(4-nitrophenyl) phosphorochloridothioate 
• 66084-67-1 2-chloro-4H-1,3,2-benzodioxaphosphorin 2-sulfide 
• 90-02-8 salicylaldehyde 

Downstream Products

• 3735-80-6 salioxon 

Relevant articles and documents

Pesticidal composition containing a microencapsulated organo-phosphorus or carbamate in a pyrethroid dispersion

An insecticidal and/or acaricidal and/or nematicidal composition having a rapid efficacy and residual activity which comprises a mixture of a poorly water-soluble organophosphorus insecticide and/or acaricide and/or nematicide and/or a poorly water-soluble carbamate insecticide and/or acaricide which have been microencapsulated in water-insoluble polymer coatings with a dispersing agent used in forming a microcapsule part, with a poorly water-soluble pyrethroid insecticide and/or acaricide emulsified or suspended in water with the above-mentioned dispersing agent used in forming a flowable part.

Synthesis of Optically Active Cyclic Phosphorothionates and Phosphoramidothionates with Insecticidal Activity by Using a Chiral Phosphorylating Agent

Chiral methyl p-nitrophenyl phosphorochloridothionate (MNPC) was utilized as a phosphorylating agent in the synthesis of optically active cyclic phosphorus esters including the enantiomers of 2-methoxy-4H-1,3,2-benzodioxaphosphorin 2-sulfide (salithion) and four diastereomers of 4-isobutyl-2-methoxy-1,3,2-oxazaphospholidine 2-sulfide (BMOS).Their insecticidal activity decreased in the following order; (S) > (R) in salithion and (S)P(S)C > (S)P(R)C > (R)P(R)C > (R)P(S)C in BMOS.