38152-42-0Relevant academic research and scientific papers
Synthesis of Pinacol Silylethers from Aromatic Aldehydes via α-Siloxybenzyliron Complexes
Vargas, Roy M.,Hossain, M. Mahmun
, p. 2727 - 2728 (1993)
Quantitative synthesis of pinacol ethers 4, 2 (X = H, Me, OMe or Cl) from the α-siloxybenzyliron complexes, 3 is reported.The iron dimer, 5 was the only other product which was reused for the reaction.
Reductive pinacol coupling of aromatic carbonyl compounds catalytic in chromium(II)
Svato?, Ale?,Boland, Wilhelm
, p. 549 - 551 (2007/10/03)
Reductive coupling of aromatic and heteroaromatic aldehydes and ketones bearing different functional groups to pinacols is effectively catalysed with 1-5 mol % of Cr(II) salts or chromocene in THF/DMF mixtures in the presence of manganese powder and trialkyl chlorosilanes. Excellent dl selectivity can be achieved albeit with lower yield using trialkylsilyl chlorides with bulky substituents.
Reductive Coupling of Carbonyl Compounds with Zinc and Trimethylchlorosilane To Produce O-Silylated Pinacols. Effect of Ultrasonic Waves
So, Jeung-Ho,Park, Moon-Kyeu,Boudjouk, Philip
, p. 5871 - 5875 (2007/10/02)
Trimethylchlorosilane reacts with carbonyl compounds in the presence of zinc to give O-silylated pinacols, vicinal bis(trimethylsiloxy)alkanes, in good yields via reductive dimerization.This is very mild route to bis(siloxy)alkanes, which are easily converted to pinacols or pinacolones in excellent yields.Electron-donating groups accelerate coupling while electron-withdrawing groups have an inhibiting effect.Cross-coupling reactions yield a mixture of bis(siloxy)alkanes.Ultrasonic irradiations of these reactions increases the yields up to 50percent compared to stirring at the same temperature.
