38156-66-0Relevant academic research and scientific papers
Total Synthesis of Aurofusarin: Studies on the Atropisomeric Stability of Bis-Naphthoquinones
Qi, Chao,Wang, Wenyu,Reichl, Kyle D.,McNeely, James,Porco, John A.
supporting information, p. 2101 - 2104 (2018/02/06)
An efficient annulation involving pyrone addition to a quinone and Dieckmann condensation was developed for rapid assembly of a γ-naphthopyrone monomeric precursor to the bis-naphthoquinone natural product aurofusarin. Dimerization was achieved through Pd
Cytotoxic calanquinone A from Calanthe arisanensis and its first total synthesis
Lee, Chia-Lin,Nakagawa-Goto, Kyoko,Yu, Donglei,Liu, Yi-Nan,Bastow, Kenneth F.,Morris-Natschke, Susan L.,Chang, Fang-Rong,Wu, Yang-Chang,Lee, Kuo-Hsiung
supporting information; experimental part, p. 4275 - 4277 (2009/04/06)
Calanquinone A (1) was isolated from an EtOAc-soluble extract of Calanthe arisanensis through bioassay-guided fractionation. Its structure was identified by spectroscopic methods. Compound 1 showed potent cytotoxicity (EC50 0.5 μg/mL) against
Evaluation of some preparations of trialkoxyphthalic acid derivatives
Parker, Kathlyn A.,Spero, Denice M.,Koziski, Kathleen A.
, p. 183 - 188 (2007/10/02)
Several approaches to trialkoxyphthalic acid derivatives, potential intermediates in a fredericamycin synthesis, were tested. Sequences based on a Diels-Alder/retro Diels-Alder reaction, a cyanide addition to a quinone, an Elbe oxidation, and an amide-directed ortho-lithiation are discussed in terms of length, yields, convenience, and the versatility of the product of each.
