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N-N-Butyl-N-Butan-4-ol-Nitrosamine, also known as N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN), is a nitrosamine compound characterized by its dark red liquid appearance. It is a potent carcinogen that specifically induces high-grade, invasive cancers in the urinary bladder of mice without affecting any other tissues.

3817-11-6

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3817-11-6 Usage

Uses

Used in Pharmaceutical Research:
N-N-Butyl-N-Butan-4-ol-Nitrosamine is used as a research chemical for inducing histologically relevant aggressive urinary bladder cancer in animal models. This application is crucial for understanding the mechanisms of bladder cancer development and progression, as well as for testing potential therapeutic interventions.
Used in Cancer Research:
In the field of cancer research, N-N-Butyl-N-Butan-4-ol-Nitrosamine serves as a valuable tool for studying the etiology and pathogenesis of urinary bladder cancer. Its ability to selectively induce high-grade, invasive cancers in the urinary bladder of mice makes it an essential compound for investigating the molecular and cellular processes underlying this specific type of cancer.
Used in Toxicology Studies:
N-N-Butyl-N-Butan-4-ol-Nitrosamine is also utilized in toxicology studies to evaluate the potential carcinogenic effects of various substances and their mechanisms of action. By exposing animals to N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE, researchers can gain insights into the toxicological properties of other chemicals and their potential to cause cancer in the urinary bladder.

Air & Water Reactions

Water soluble.

Reactivity Profile

A hydroxylated and nitrated amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Biochem/physiol Actions

Carcinogen used to induce urinary bladder cancer in animal models. The result of exposure is histologically comparable to human urinary bladder tumorigenesis. Used in chemopreventative studies.

Check Digit Verification of cas no

The CAS Registry Mumber 3817-11-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,1 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3817-11:
(6*3)+(5*8)+(4*1)+(3*7)+(2*1)+(1*1)=86
86 % 10 = 6
So 3817-11-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H18N2O2/c1-2-3-6-10(9-12)7-4-5-8-11/h11H,2-8H2,1H3

3817-11-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name N-butyl-N-(4-hydroxybutyl)nitrous amide

1.2 Other means of identification

Product number -
Other names 4-Hydroxybutylbutylnitrosamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3817-11-6 SDS

3817-11-6Relevant academic research and scientific papers

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