38176-72-6

Upstream product

• 69477-35-6 dichloro-(2,4-dichloro-phenoxy)-phosphine 
• 120-83-2 2,4-dichlorophenol 

Downstream Products

• 18351-18-3 O-ethyl-O-(2,4-dichlorophenyl)thiophosphorochloride 
• 97-17-6 dichlofenthion 
• 2595-57-5 amidothiophosphoric acid O-ethyl ester-O'-(2,4-dichloro-phenyl ester) 
• 349536-75-0 O-(2,4-dichlorophenyl) dihydrazinothiophosphinate 

Relevant academic research and scientific papers

In search of new organophosphorus pesticides and insecticides. Part III: Synthesis and anticholinesterase studies of 3-(subs)-quinoxy/pyridinoxy/cyclica mino-2,3-dihydro-2-(4-chlorophenyl)-1H-naphth [1,2-E][1,3,2] oxazaphosphorine 3-sulfides

In situ treatment of (cyclic) amino derivatives with the product obtained from the cyclocondensation of 1-p-chloroanilinomethyl naphthol-2 and thiophosphoryl chloride in dry benzene-THF afforded the titled oxazaphosphorine sulfides in good yield. Subsequently, the reaction of pyridinoxy/quinoxythiophosphorodi chloridates and 1-p-chloro anilino methyl naphthol-2 in dry benzene-THF mixture gave the corresponding pyridinoxy/quinoxy oxaza phosphorine 3-sulfides in quantitative yield. All the condensations proceeded smoothly by employing triethylamine to scavenge the liberated hydrogen chloride gas. Anticholinestease studies of these compounds indicated very high degree of inhibition several times higher than the reference standard-methyl parathion.

Photolysis, oxidation, and hydrolysis of 14C-ethyl prothiofos [O-(2, 4-dichlorophenyl) O-ethyl S-propyl phosphorodithioate]

The chemical stability of the widely used organophosphorus insecticide 14C-prothiofos was studied. For this study prothiofos insecticide and some of its degradation products have been prepared. The oxon of the parent compound was obtained through the oxidation of the insecticide with various oxidizing agents, where yields depended on the type and nature of oxidizing agent. The effect of ultraviolet light and direct sunlight on prothiofos were investigated. Exposure to direct sunlight caused gradual degradation of prothiofos giving the same products as UV irradiation.The hydrolysis of 14C-prothiofos at pH 5, 7, 8, and 9 in buffered aqueous media at 25C, 40C and 55C was studied. The results indicated that prothiofos was stable in acid medium, but it was hydrolyzed to 2,4-dichlorophenol and O-ethyl S-propyl phosphorodithioate in alkaline medium.The degradation products identified by TLC and GC/MS were prothiofos oxon, O-ethyl S-propyl phosphordithioate, des-propyl thioprothiofos, prothiofos oxon sulfoxide, and one unknown compound in addition to the parent compound. The phenolic compound was identified by GC/MS and by its color.Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright Taylor & Francis Group, LLC.

Distribution and degradation of 14C-ethyl prothiofos in a potato plant and the effect of processing

Prothiofos and some of its degradation products have been synthesized in our laboratory for investigation purposes. The residual fate of 14C-ethyl prothiofos in different parts of potato plant was studied. The highest level of insecticide residues was detected in and on the leaves of potato plants. The residues of prothiofos insecticide were mainly located in the peels of potato tubers (peeling process removed 85% of the total residue after one month of the treatment), small amount penetrated into the pulp of potato tubers. The degradation products in the extracts of both peel and pulp of potato tubers were identified as prothiofos, prothiofos oxon, desethyl prothiofos, O-ethyl-S-propyl phosphorodithioate, O-ethyl phosphorothioate, O-ethyl-S-propyl phosphoric acid, O-ethyl phosphoric acid, despropylthio prothiofos, and prothiofos oxon sulfoxide. In addition 2,4-dichlorophenol was identified as such and in conjugated metabolites. Potatoes are processed in three ways: frying, boiling, and baking, which is simulated in home preparation. The amount of prothiofos residues was found to decrease on boiling (70%) and further on baking (82%) and frying (100%). The results indicated that frying process is the most effective method for reducing the amount of pesticide residues. Detectable residues were found in boiled potatoes (2.64 ppm), in the boiling water (0.24 ppm), and in the frying oil (0.71 ppm). From these results we concluded that the processed potatoes are safely used for human consumption. Copyright Taylor & Francis Group, LLC.

The synthesis of N-(glycosylthioureylene)-aminothiophosphonic and -diaminothiophosphinic O-aryl esters

Reactions of O-aryl dihydrazinothiophosphinates (4, 5) or O,O′-diaryl hydrazinothio-phosphonates (2) with glycosyl isocyanates (6) gave corresponding N-(glycosylthioureylene)-aminothiophosphonic and -diaminothiophosphinic O-aryl esters. Their structures w

Thermal and spectral studies on cellulose arylthiophosphates in air

The thermal behaviour of cellulose and cellulose arylthiophosphate samples have been studied using DTA and TG techniques from ambient temperature to 600°C in static air atmosphere. First exotherm in DTA curves of cellulose arylthiophosphate samples caused