38177-07-0

Basic information

• Product Name: 5-nitroisophthaldiamide
• Synonyms: 5-nitroisophthaldiamide;5-Nitro-1,3-benzenedicarboxamide;5-nitrobenzene-1,3-dicarboxamide
• CAS NO: 38177-07-0
• Molecular Formula: C₈H₇N₃O₄
• Molecular Weight: 209.15888
• EINECS: 253-811-9
• Mol File: 38177-07-0.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 370.1°Cat760mmHg
• Flash Point: 177.6°C
• Appearance: /
• Density: 1.508g/cm³
• Vapor Pressure: 1.13E-05mmHg at 25°C
• Refractive Index: 1.651
• CAS DataBase Reference: 5-nitroisophthaldiamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-nitroisophthaldiamide(38177-07-0)
• EPA Substance Registry System: 5-nitroisophthaldiamide(38177-07-0)

Safety Data

• Hazardous Substances Data: 38177-07-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H7N3O4/c9-7(12)4-1-5(8(10)13)3-6(2-4)11(14)15/h1-3H,(H2,9,12)(H2,10,13)

Upstream product

• 618-88-2 5-nitrobenzene-1,3-dicarboxylic acid 
• 13438-30-7 5-nitro-1,3-benzenedicarbonylchloride 

Downstream Products

• 57369-97-8 5-aminoisophthalonitrile 
• 1448347-64-5 (2S)-N-(1-(2-Chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(3,5-dicyanophenyl)-5-oxopyrrolidine-2-carboxamide 
• 1448348-39-7 5-((2S)-N-(1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyano pyridin-2-yl)-5-oxopyrrolidine-2-carboxamido)isophthalamide 
• 28321-49-5 1-aminobenzene-3,5-dicarboxylic acid diamide 
• 108761-80-4 2,6-dicyano-p-phenylenediamine 
• 33224-18-9 5-nitrobenzene-1,3-dicarbonitrile 
• 41642-51-7 D₇ 
• 20033-48-1 1-amino-2,6-dicyano-4-nitrobenzene 

Relevant articles and documents

Corresponding amine nitrile and method of manufacturing thereof

The present invention relates to a nitrile manufacturing method, which has characteristics of significantly-reduced ammonia source consumption, low environmental pressure, low energy consumption, low production cost, high nitrile purity, high nitrile yield and the like compared with the method in the prior art, wherein nitrile having a complicated structure can be obtained through the method. The present invention further relates to a method for producing a corresponding amine from the nitrile.

Corresponding amine nitrile and method of manufacturing thereof (by machine translation)

The invention relates to a method of manufacturing one kind of nitrile, compared with the prior art, has significantly reduced the amount of ammonia, the environmental pressure of the small, low energy consumption, low production cost, nitrile product purity and yield and the like, and can obtain more complex structure of the nitriles. The invention also relates to the corresponding amine by the nitrile manufacture method. (by machine translation)

THERAPEUTICALLY ACTIVE COMPOUNDS AND USE THEREOF

Provided are therapeutically active compounds and the use in manufacture of medicaments for treating a cancer characterized by the presence of a mutant allele of IDH1.