38186-54-8

Basic information

• Product Name: 1,2,3,4-TETRAHYDRO-9-ACRIDINECARBOXYLIC ACID DIHYDRATE
• Synonyms: 1,2,3,4-TETRAHYDRO-9-ACRIDINECARBOXYLIC ACID DIHYDRATE;1,2,3,4-TETRAHYDROACRIDINE-9-CARBOXYLIC ACID DIHYDRATE;1,2,3,4-TETRAHYDROACRIDINE-9-CARBOXYLIC ACID HYDRATE;1,2,3,4-TETRAHYDROACRIDINE-9-CARBOXYLIC ACID HYDRATE 96%;1,2,3,4-tetrahydro-9-acridinecarboxylic acid hydrate;1,2,3,4-Tetrahydroacridine-9-carboxylic acidhydrate,96%;1,2,3,4-tetrahydroacridine-9-carboxylic acid(SALTDATA: FREE);,2,3,4-TETRAHYDRO-9-ACRIDINECARBOXYLIC ACID DIHYDRATE
• CAS NO: 38186-54-8
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.26
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 38186-54-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 284-288 °C(lit.)
• Boiling Point: 421°C at 760 mmHg
• Flash Point: 208.4°C
• Appearance: /
• Density: 1.29g/cm³
• Vapor Pressure: 7.72E-08mmHg at 25°C
• Refractive Index: 1.671
• PKA: 1.15±0.20(Predicted)
• CAS DataBase Reference: 1,2,3,4-TETRAHYDRO-9-ACRIDINECARBOXYLIC ACID DIHYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-TETRAHYDRO-9-ACRIDINECARBOXYLIC ACID DIHYDRATE(38186-54-8)
• EPA Substance Registry System: 1,2,3,4-TETRAHYDRO-9-ACRIDINECARBOXYLIC ACID DIHYDRATE(38186-54-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 38186-54-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H13NO2/c16-14(17)13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H,16,17)

Upstream product

• 91-56-5 indole-2,3-dione 
• 108-94-1 cyclohexanone 
• 42878-53-5 1,2,3,4-tetrahydro-acridine-9-carboxylic acid amide 

Downstream Products

• 260-94-6 acridine 
• 55618-86-5 methyl-[(1,2,3,4-tetrahydro-9-yl)acridine]carboxylate 
• 6854-08-6 1,2,3,4-tetrahydro-9-acridinecarboxaldehyde 

Relevant articles and documents

Synthesis of substituted 4-([1,2,4]triazolo[3,4-b]-[1,3,4]thiadiazol-6-yl) quinolines

4-Amino-5-R1-4H-1,2,4-triazole-3-thiols react with 2-R 2-6-R3-quinoline-4-carboxylic acids in phosphoryl chloride to give 2-R2-6-R3-4-(3-R1-[1,2,4]triazolo[3,4- b][1,3,4]thiadiazol-6-yl)qui

Synthesis and Luminescent Properties of Eu3+, Gd3+, and Tb3+ Complexes with Quinoline-4-carboxylic Acids

New complex compounds LnL3·nH2O (n = 5–10) have been synthesized on the basis of Eu3+, Gd3+, and Tb3+ salts and quinoline-4-carboxylic acid derivatives obtained via the Pfitzinger reaction. Compositio

Quinoline-4-methyl esters as human nonpancreatic secretory phospholipase A2 inhibitors

A series of novel fused heterocycle methyl esters were designed and synthesized as human nonpancreatic secretory phospholipase A2 (hnps-PLA2) competitive inhibitors. Among the 22 synthesized compounds, 17 quinoline-4-methyl esters displayed hnps-PLA2 inhibition activity in the in vitro bioassay. The IC50 value for the best compound 3o was 1.5 μM. The structure-inhibition-activity relationships of the compounds were studied using molecular docking.