42878-53-5 Usage
Uses
Used in Pharmaceutical Industry:
1,2,3,4-Tetrahydro-acridine-9-carboxylic acid amide is used as a potential therapeutic agent for neurodegenerative diseases due to its ability to inhibit the aggregation of amyloid beta proteins, which are implicated in the development of Alzheimer's disease.
Used in Neuroprotective Agents:
1,2,3,4-TETRAHYDRO-ACRIDINE-9-CARBOXYLIC ACID AMIDE is utilized as a neuroprotective agent because of its antioxidant and neuroprotective properties, which may contribute to the development of novel therapeutics for neurodegenerative disorders.
Further research is necessary to fully understand the biological and therapeutic properties of 1,2,3,4-tetrahydro-acridine-9-carboxylic acid amide, with the aim of advancing its potential use in clinical applications for the treatment of neurodegenerative conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 42878-53-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,8,7 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 42878-53:
(7*4)+(6*2)+(5*8)+(4*7)+(3*8)+(2*5)+(1*3)=145
145 % 10 = 5
So 42878-53-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H14N2O/c15-14(17)13-9-5-1-3-7-11(9)16-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,15,17)
42878-53-5Relevant academic research and scientific papers
Synthesis of 9-Amino-, 9-Aminomethyl-1,2,3,4-tetrahydro- And 1,2,3,4,5,6,7,8-Octahydroacridine Derivatives
Del Giudice, Maria Rosaria,Borioni, Anna,Mustazza, Carlo,Gatta, Franco
, p. 1661 - 1667 (2007/10/03)
This paper describes the synthesis of 9-amino-2- and 4-hydroxy- and 2,4-dihydroxy-1,2,3,4-tetrahydroacridines 2 and of 9-amlnomethyl-1,2,3,4-tetrahydro- and 1,2,3,4,5,6,7,8-octahydroacridines 3 starting from the corresponding 9-carboxamido derivatives. A
Synthesis, Pharmacological Activities and Physico-chemical Properties of 4-(Substituted amino/N4-arylpiperazinyl/aminocarbonyl)-2, 3-polymethylenequinolines
Bindra, Jasjit S.,Rastogi, Shri Nivas,Patnaik, G. K.,Anand, N.,Rao, K. G. Gurudath,et al.
, p. 318 - 329 (2007/10/02)
A series of N-substituted-aminoacridines (27-29) and 4-(substituted amino, N4-arylpiperazinyl and aminocarbonyl)-2,3-polymethylenequinolines (30-103) have been synthesized and tested for their CNS effects.Compounds with significant activity hav
