38201-61-5

Usage

Uses

Used in Pharmaceutical Industry:
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-methyl-2-thio is used as a potential pharmaceutical candidate for [specific application reason, if available] due to its heterocyclic nature and the presence of a thio group, which may allow it to interact with biological systems in unique ways. The sulfur content could also provide distinct chemical properties that are beneficial for drug development.
Used in Biological Research:
In the field of biological research, (1)benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-methyl-2-thio may be utilized as a compound of interest for studying its interactions with biological systems, potentially leading to the discovery of new mechanisms of action or therapeutic targets. Its complex molecular structure and heterocyclic nature make it a promising subject for investigation.

InChI:InChI=1/C11H12N2OS2/c1-13-10(14)8-6-4-2-3-5-7(6)16-9(8)12-11(13)15/h2-5H2,1H3,(H,12,15)

Upstream product

• 51486-13-6 2-(3-Methyl-thioureido)-4,5,6,7-tetrahydrobenzothiophen-3-carbonsaeureethylester 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 556-61-6 methyl thioisocyanate 
• 85716-87-6 ethyl 2-isothiocyanato-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 74-89-5 methylamine 
• 4651-91-6 3-cyano-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene 
• 126105-75-7 4-Imino-3-methyl-3,4,5,6,7,8-hexahydro-1H-benzo[4,5]thieno[2,3-d]pyrimidine-2-thione 
• 38201-62-6 2-amino-3-(N-methylcarboxamido)-4,5,6,7-tetrahydrobenzothiophene 
• 17356-08-0 thiourea 

Downstream Products

• 59898-79-2 (3-methyl-4-oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-acetic acid ethyl ester 
• 59898-74-7 (3-methyl-4-oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-acetic acid 
• 337349-66-3 3-methyl-2-(prop-2-yn-1-ylthio)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one 
• 79587-91-0 (3-Methyl-4-oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-phenyl-acetic acid 
• 79598-26-8 3a-Ethoxy-4-methyl-2-phenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione 

Relevant academic research and scientific papers

REACTIONS WITH ETHYL-4,5,6,7-TETRAHYDRO-2-ISOTHIOCYANATO-1-BENZOTHIOPHENE-3-CARBOXYLATE. SYNTHESIS OF SOME NOVEL HETEROCYCLIC COMPOUNDS WITH POTENTIAL HYPNOTIC ACTIVITY

Ethyl-4,5,6,7-tetrahydro-2-isothiocyanato-1-benzothiophene-3-carboxylate (2), prepared from ethyl-4,5,6,7-tetrahydro-2-amino-1-benzothiophene-3-carboxylate (1) by the thiophosgene method, was converted with nucleophiles into benzothienopyrimidine derivatives (3-5) and (7) either directly or through thiourethane (6a).The tricyclic, benzothienopyrimidine system (8) and (9) were obtained either from the isothiocyanate (2) or the thiourethane (6a), while the tetracyclic systems, triazolothienopyrimidines (10,11); tetrazolothienopyrimidines (12,13) and tetrazepino derivative (14), were obtained from 2,3,5,6,7,8-hexahydro-3-amino-2-hydrazino-1-benzothienopyrimidine-4(3H)-one (9).Preliminary pharmacological screening revealed that some of the new compounds exhibited hypnotic activity. - Key words: Thienopyrimidines; hypnotic activity

Synthesis and pharmacological activities of some 3-substituted thienopyrimidin-4-one-2-thiones

The condensation of substituted 2-amino-3-carbethoxy-thiophenes with methyl, ethyl and phenyl isothiocyanate yields the corresponding thienylthioureas which cyclize in ethanol saturated with dry hydrochloric acid to form 3-substituted thienopyrimid

Interaction of heterothiocumulenes with 2-amino-3-cyanothiophenes: Formation of thienopyrimidines

Thieno-fused(1,3)-thiazine, 4-imino-2-thioxo-2,4-dihydro-1H-thieno(1,3)-thiazine (2) has been directly synthesised by the reaction of o-aminonitrile (1a) with carbon disulphide.Thiazine (2) on reaction with primary aromatic amines leads to thieno2

Studies on Fused-ring Mesoionic Thiazolothienopyrimidine Systems

Cyclodehydration of 2-carboxymethylmercaptothienopyrimidin-4(3H)-ones (IV) have been studied.IV (R3=R4=Ph and R3=Me,R4=Ph) on reaction with acetic anhydride and pyridine mixture readily yield stable fusedring mesoionic systems (VI).While IV (R3=Ph,

Synthesis of 3 substituted thieno[2,3 d]pyrimidin 4(3H) one 2 mercaptoacetic acids and their ethyl esters for pharmacological screening

3 Substituted thieno[2,3 d]pyrimidin 4(3H) one 2 mercaptoacetic acids and their ethyl esters were synthesized from 2 mercaptothieno[2,3 d]pyrimidin 4 (3H) ones, which were obtained by cyclization of thienylthioureas in acidic medium. Analgesic, anti inflammatory, and anticonvulsant activities were found in some of these compounds. Significant antimicrobial activity was exhibited by thienylthioureas.