38210-45-6

Upstream product

• 758640-21-0 N-Benzylaniline 
• 612-98-6 N-benzyl-N-phenylnitrous amide 
• 95-15-8 Benzo[b]thiophene 
• 98437-23-1 benzo[b]thiophene-2-boronic acid 
• 615-43-0 2-iodophenylamine 
• 615-36-1 2-bromoaniline 
• 577-19-5 2-nitrophenyl bromide 

Downstream Products

• 1609211-27-9 C₂₀H₁₄N₂OS 
• 239-35-0 11-thiabenzo[a]fluorene 
• 1207-95-0 2-phenylbenzo[b]thiophene 
• 1367458-53-4 6-phenylbenzo[b]naphtho[2,1-d]thiophene 

Relevant academic research and scientific papers

Fluorescent chemosensor for Al(III) based on chelation-induced fluorescence enhancement and its application in live cells imaging

A tridentate Schiff base receptor BPB was synthesized by condensation of 2-(benzo[b]thiophen-2-yl)benzenamine with salicylaldehyde in ethanolic medium and characterized by various spectral (FT-IR, 1H NMR, 13C NMR and mass) data. The methanolic solution of BPB was applied for the fluorescent sensing of metal ions dissolved in aqueous medium. The selectivity experiment revealed that the receptor BPB showed significant fluorescence enhancement at 430 nm in the presence of A(III) due to the chelation-induced fluorescence enhancement (CHEF) mechanism. Receptor BPB formed complex with Al(III) in 2:1 binding ratio with the estimated binding constant of K = 3.02 × 108 M?2. Without any interference from other tested metal ions, the receptor BPB can detect the concentration of Al(III) down to 256 nM. The receptor BPB showed good cell permeability and was applied for the qualitative and quantitative detection of intracellular Al(III) in A549 cell line (adenocarcinomic human alveolar basal epithelial cells) by using a confocal imaging technique.

B2N2-Embedded Polycyclic Aromatic Hydrocarbons with Furan and Thiophene Derivatives Functionalized in Crossed Directions

A series of polycyclic aromatic hydrocarbons (PAHs), consisting of two pairs of BN units, have been designed and their synthesis has been achieved by electrophilic C?H borylation. Two conjugation extension directions can be found in these B2Ns

Direct photoexcitation of benzothiazolines: Acyl radical generation and application to access heterocycles

An acyl radical generation and functionalization strategy through direct photoexcitation of benzothiazolines has been developed. The formed acyl radical species can either be trapped by quinoxalin-2-ones to realize their C(3)-H functionalization or trigger a cascade radical cyclization with isonitriles to synthesise biologically important phenanthridines. The synthetic value of this protocol can be further illustrated by the modification of quinoxalin-2-ones, containing important natural products and drug-based complex molecules.

Rhodium-catalyzed oxidative C-H/C-H cross-coupling of aniline with heteroarene: N-nitroso group enabled mild conditions

The development of transition metal-catalyzed oxidative C-H/C-H cross-coupling between two (hetero)arenes to forge aryl-heteroaryl motifs under mild conditions is an appealing yet challenging task. Herein, we disclose a rhodium-catalyzed oxidative C-H/C-H cross-coupling reaction of an N-nitrosoaniline with a heteroarene under mild conditions. The judicious choice of the N-nitroso group as a directing group enables heightened reactivity. The coupled products could be transformed expediently to (2-aminophenyl)heteroaryl skeletons.

Photochemical intramolecular amination for the synthesis of heterocycles

Polycyclic heterocycles can be formed in good to excellent yields via photochemical conversion of the corresponding substituted aryl azides under irradiation with purple LEDs in a continuous flow reactor. The experimental set-up is tolerant to UV-sensitive functional groups while affording diverse carbazoles, as well as an indole and pyrrole framework, in short reaction times. The photochemical method is presumed to progress through a mechanism differing from the other methods of azide activation involving transition metal catalysis.

Radical (Phenylsulfonyl)difluoromethylation of Isocyanides with PhSO2CF2H under Transition-Metal-Free Conditions

An atom-economical method for radical (phenylsulfonyl)difluoromethylation of isocyanides with PhSO2CF2H under transition-metal-free conditions has been developed. A PhSO2CF2 radical is generated through the oxidation of PhSO2CF2- after the deprotonation of PhSO2CF2H in one pot. The reaction exhibits excellent functional-group tolerance and the resulting products can be further modified with the removal of a PhSO2 group to give other CF2-containing compounds.

Radical Fluoroalkylation of Isocyanides with Fluorinated Sulfones by Visible-Light Photoredox Catalysis

The radical fluoroalkylation of isocyanides with fluorinated sulfones is enabled by visible-light photoredox catalysis. A wide range of readily available mono-, di-, and trifluoromethyl heteroaryl sulfones can thus be used as efficient radical fluoroalkylation reagents under mild conditions. This method not only describes a new synthetic application of fluorinated sulfones, but also provides a new route to fluoroalkyl radicals.

HETERO-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME

In the present invention, provided are: a heterocyclic compound which can significantly extend lifespan and improve efficiency, electrochemical stability, and thermal stability of the organic light-emitting device; and an organic light-emitting device containing the heterocyclic compound in an organic compound layer. The heterocyclic compound is represented by chemical formula 1.COPYRIGHT KIPO 2016

Visible-light-induced regioselective synthesis of polyheteroaromatic compounds

A method for visible-light-induced synthesis of polyheteroaromatics from 2-heteroaryl-substituted anilines and heteroarylalkynes was developed. The process, which uses fac-Ir(ppy)3 as the photocatalyst and tBuONO as the diazotization reagent, is highly regioselective.

MeOTf- and TBD-Mediated Carbonylation of ortho-Arylanilines with CO2 Leading to Phenanthridinones

Carbonylation of o-arylanilines utilizing CO2 as a carbonyl source for the synthesis of important phenanthridinones with a free (NH)-lactam motif has been described under metal-free condition. A range of o-arylanilines were transformed to the corresponding phenanthridinones in high yields.