382135-53-7Relevant academic research and scientific papers
Design of selective and soluble inhibitors of tumor necrosis factor-α converting enzyme (TACE)
Rabinowitz,Andrews,Becherer,Bickett,Bubacz,Conway,Cowan,Gaul,Glennon,Lambert,Leesnitzer,McDougald,Moss,Musso,Rizzolio
, p. 4252 - 4267 (2007/10/03)
A program to improve upon the in vitro, in vivo, and physicochemical properties of N-hydroxyformamide TACE inhibitor GW 3333 (1) is described. Using the primary structure of pro-TNF-α, along with a homology model of the catalytic domain of TACE based on t
