38223-06-2

Usage

Uses

Used in Organic Synthesis:
4-(2-Dimethylaminoethyl)pyridine is utilized as a catalyst in organic synthesis, facilitating various chemical reactions and improving the efficiency of the synthesis process.
Used in Pharmaceutical and Agrochemical Industries:
It serves as a building block for the synthesis of a range of pharmaceuticals and agrochemicals, contributing to the development of new drugs and agricultural products.
Used in Plastics Production:
4-(2-Dimethylaminoethyl)pyridine is used as a stabilizer in the production of plastics, enhancing the durability and performance of the final plastic products.
Used in Dyes and Pigments Production:
This chemical acts as an intermediate in the production of dyes and pigments, playing a crucial role in the coloration and appearance of various materials.
Used as a Corrosion Inhibitor:
4-(2-Dimethylaminoethyl)pyridine is employed as a corrosion inhibitor, protecting metal surfaces from degradation and extending their service life.
Used as an Insect Repellent:
It can be used as an insect repellent, helping to deter and protect against insect infestations.
Used in Surfactant Production:
Additionally, 4-(2-Dimethylaminoethyl)pyridine is used in the production of some types of surfactants, which are essential in various cleaning and industrial applications.
Safety Precautions:
It is important to handle 4-(2-Dimethylaminoethyl)pyridine with care, as it can be irritating to the skin, eyes, and respiratory system. Prolonged exposure may lead to allergic reactions, and appropriate safety measures should be taken during its use.

InChI:InChI=1/C9H14N2/c1-11(2)8-5-9-3-6-10-7-4-9/h3-4,6-7H,5,8H2,1-2H3

Upstream product

• 100-43-6 4-vinylpyridine 
• 124-40-3 dimethyl amine 
• 506-59-2 N,N-dimethylammonium chloride 

Downstream Products

• 102308-48-5 N,N-dimethyl-2-(4-piperidinyl)ethanamine 

Relevant academic research and scientific papers

The catalytic effect of anion-exchanged supported ionic liquid on aza-Michael-type addition

Abstract: An effective synthesis of anion-exchanged supported ionic liquids using diatomaceous earth as solid support and its catalytic effect on the aza-Michael-type addition is described. Anionic polytungstophosphate and bisulfate ion are used in the anion-exchange step in catalyst design. In addition, the aza-Michael-type addition of various amines to 2- and 4-vinyl pyridine was examined in this article. The catalytic system can be separated from the reaction mixture and recycled in subsequent reactions. The structure of anion-exchanged supported ionic liquid on diatomaceous earth was studied by XRD, FT-IR, SEM, TGA and BET techniques. The structure of organic products was determined by 1HNMR, 13CNMR, FTIR, CHN and MASS spectroscopy. Graphical Abstract: [Figure not available: see fulltext.].

Aza-Michael-type addition reaction catalysed by a supported ionic liquid phase incorporating an anionic heteropoly acid

In this work, we have obtained substituted amines under mild conditions in good yields using the Aza-Michael-type addition of various amines to vinyl compounds catalysed by a supported ionic liquid incorporating an anionic heteropoly acid. Different catalysts, including Lewis acids, Br?nsted acids and heteropoly acids were investigated in which heteropoly acids having dual Br?nsted and Lewis acid characteristics were excellent catalysts. The ionic liquid incorporating a polytungstate anion supported on magnetic diatomaceous earth as a magnetically separable heterogeneous catalyst offered the best results in terms of yield. The solid nanocatalyst was easily removed with a magnet.

Homoazanicotine: A structure-affinity study for nicotinic acetylcholine (nACH) receptor binding

We have recently identified 3-[(1-methyl)-4,5-dihydro-1H-imidazol-2-yl)methyl]pyridine (homoazanicotine, 8) as a novel nicotinic acetylcholinergic (nACh) receptor ligand. In the present investigation, after we determined that 8 binds selectively at nicoti

Chemical Behaviour of Trimethylammonium N-Methylides Substituted with Nitrogen-containing Heteroaromatic Rings. Rearrangement of N,N-Dimethyl(pyridylmethyl)ammonium, N,N-Dimethyl-(1-methylpyrrolylmethyl)ammonium and N,N-Dimethyl-(1-methylindolylmethyl)ammonium N-Methylides

N,N-Dimethyl(pyridylmethyl)ammonium N-methylides 2, 6 11, N,N-dimethyl(1-methylpyrrolylmethyl)ammonium N-methylides 15, 20, and N,N-dimethyl(1-methylindolylmethyl)ammonium N-methylides 23, 28 were generated by fluoride ion-induced desilylation of the corresponding (trimethylsilyl)methylammonium salts 1, 5, 10, 14, 19, 22 and 27, and the isomerisation products of the ylides were investigated.

Synthesis and structure-activity relationship of some 5- [[[(dialkylamino)alkyl]-1-piperidinyl]acetyl]-10,11-dihydro-5H- benzo[b,e][1,4]diazepin-11-ones as M2-selective antimuscarinics

A series of 5-[[[(dialkylamino)alkyl]-1-piperidinyl]acetyl]-10,11-dihydro- 5H-dibenzo[b,e][1,4]-diazepin-11-ones were prepared as potential M2- selective ligands. The compounds were evaluated for their affinity and selectivity for the muscarinic cholinergic receptor. The best M2-selective antimuscarinic agent studied is 5-[[4-[4-(diethylamino)butyl]-1- piperidinyl]acetyl]-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-11-one, which is approximately 10 times more potent at M2 receptors than previously known compounds such as 11-[[4-[4-(diethylamino)butyl]-1-piperidinyl]acetyl]-5,11- dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one (AQ-RA 741).